Results 51 to 60 of about 356,969 (310)

Optimal control with adaptive weighting coefficients for integrated vehicle dynamics control [PDF]

International Journal of Advanced Design and Manufacturing Technology, 2014
: In this work, an optimal control scheme with adaptive weighting coefficients is presented which coordinates different vehicle dynamics control objectives, thus ruling out possible conflicts among them.
naser esmaeili, S. Hamed Tabatabaei Oreh, Reza Kazemi   +2 more
doaj  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

On an Optimal -Control Problem in Coefficients for Linear Elliptic Variational Inequality

Abstract and Applied Analysis, 2013
We consider optimal control problems for linear degenerate elliptic variational inequalities with homogeneous Dirichlet boundary conditions. We take the matrix-valued coefficients in the main part of the elliptic operator as controls in .
Olha P. Kupenko, Rosanna Manzo
doaj   +1 more source

ON APPROXIMATION OF STATE-CONSTRAINED OPTIMAL CONTROL PROBLEM IN COEFFICIENTS FOR p-BIHARMONIC EQUATION

Journal of Optimization, Differential Equations and Their Applications, 2018
We study a Dirichlet-Navier optimal design problem for a quasi-linear mono- tone p-biharmonic equation with control and state constraints. The coecient of the p-biharmonic operator we take as a design variable in BV ( )\L1( ).
Peter I. Kogut, Olha P. Kupenko
doaj   +1 more source

Asymptotic analysis of optimal control problems on the semiaxes for Carathéodory differential inclusions with fast oscillating coefficients

Nonlinear Analysis, 2023
We consider an optimal control problem for a differential inclusion of the Carathéodory type affine with respect to the control with a coercive cost functional on a semiaxis and with fast oscillating time-dependent coefficients.
Sergey Dashkovskiy, Oleksiy Kapustyan, Olena Kapustian, Tetyana Zhuk   +3 more
doaj   +1 more source

A Unified Framework for STAR-RIS Coefficients Optimization

IEEE Transactions on Signal Processing
Simultaneously transmitting and reflecting (STAR) reconfigurable intelligent surface (RIS), which serves users located on both sides of the surface, has recently emerged as a promising enhancement to the traditional reflective only RIS. Due to the lack of a unified comparison of communication systems equipped with different modes of STAR-RIS and the ...
Hancheng Zhu, Yuanwei Liu, Yik-Chung Wu, Vincent K. N. Lau   +3 more
openaire   +3 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

On relaxation of state-constrained optimal control problem in coefficients for biharmonic equation

Vìsnik Dnìpropetrovsʹkogo Unìversitetu: Serìâ Modelûvannâ, 2015
We study a Dirichlet optimal control problem for biharmonic equation withcontrol and state constraints. The coecient of the biharmonic operator, the weightu, we take as a control in L1(Ω).
P. I. Kogut, L. V. Voloshko
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Optimal consumption and investment for markets with random coefficients [PDF]

Finance and Stochastics, 2012
We consider an optimal investment and consumption problem for a Black-Scholes financial market with stochastic coefficients driven by a diffusion process. We assume that an agent makes consumption and investment decisions based on CRRA utility functions.
Berdjane Belkacem, Serguei Pergamenchtchikov   +1 more
openaire   +4 more sources