Results 61 to 70 of about 8,116,877 (276)

Asymptotic analysis of optimal control problems on the semiaxes for Carathéodory differential inclusions with fast oscillating coefficients

open access: yesNonlinear Analysis, 2023
We consider an optimal control problem for a differential inclusion of the Carathéodory type affine with respect to the control with a coercive cost functional on a semiaxis and with fast oscillating time-dependent coefficients.
Sergey Dashkovskiy   +3 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Optimal control with adaptive weighting coefficients for integrated vehicle dynamics control [PDF]

open access: yesInternational Journal of Advanced Design and Manufacturing Technology, 2014
: In this work, an optimal control scheme with adaptive weighting coefficients is presented which coordinates different vehicle dynamics control objectives, thus ruling out possible conflicts among them.
naser esmaeili   +2 more
doaj  

On the Optimal Estimates and Comparison of Gegenbauer Expansion Coefficients [PDF]

open access: yesSIAM Journal on Numerical Analysis, 2014
In this paper, we study optimal estimates and comparison of the coefficients in the Gegenbauer series expansion. We propose an alternative derivation of the contour integral representation of the Gegenbauer expansion coefficients which was recently ...
Haiyong Wang
semanticscholar   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

On an Optimal -Control Problem in Coefficients for Linear Elliptic Variational Inequality

open access: yesAbstract and Applied Analysis, 2013
We consider optimal control problems for linear degenerate elliptic variational inequalities with homogeneous Dirichlet boundary conditions. We take the matrix-valued coefficients in the main part of the elliptic operator as controls in .
Olha P. Kupenko, Rosanna Manzo
doaj   +1 more source

ON APPROXIMATION OF STATE-CONSTRAINED OPTIMAL CONTROL PROBLEM IN COEFFICIENTS FOR p-BIHARMONIC EQUATION

open access: yesJournal of Optimization, Differential Equations and Their Applications, 2018
We study a Dirichlet-Navier optimal design problem for a quasi-linear mono- tone p-biharmonic equation with control and state constraints. The coecient of the p-biharmonic operator we take as a design variable in BV ( )\L1( ).
Peter I. Kogut, Olha P. Kupenko
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

On relaxation of state-constrained optimal control problem in coefficients for biharmonic equation

open access: yesVìsnik Dnìpropetrovsʹkogo Unìversitetu: Serìâ Modelûvannâ, 2015
We study a Dirichlet optimal control problem for biharmonic equation withcontrol and state constraints. The coecient of the biharmonic operator, the weightu, we take as a control in L1(Ω).
P. I. Kogut, L. V. Voloshko
doaj   +1 more source

Group analysis of a class of nonlinear Kolmogorov equations

open access: yes, 2016
A class of (1+2)-dimensional diffusion-convection equations (nonlinear Kolmogorov equations) with time-dependent coefficients is studied with Lie symmetry point of view. The complete group classification is achieved using a gauging of arbitrary elements (
E Demetriou   +9 more
core   +1 more source

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