Results 71 to 80 of about 8,116,877 (276)

Optimal Selection of Wavelet Coefficients for Electrocardiograph Compression [PDF]

ETRI Journal, 2007
This paper presents a simple method to implement a complete on-line portable wireless holter including an electrocardiogram (ECG) monitoring, processing, and communication protocol. The proposed algorithm significantly reduces the hardware resources of threshold estimation for ECG compression, using the standard deviation updated with each new input ...
Quero Reboul, José Manuel, Elena Pérez, María del Mar, Borrego, Inmaculada   +2 more
openaire   +3 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Optimal coefficients for elliptic PDEs

We consider an optimization problem related to elliptic PDEs of the form $-{\rm div}(a(x)\nabla u)=f$ with Dirichlet boundary condition on a given domain $Ω$. The coefficient $a(x)$ has to be determined, in a suitable given class of admissible choices, in order to optimize a given criterion.
Buttazzo, Giuseppe, Casado-Díaz, Juan, Maestre, Faustino   +2 more
openaire   +2 more sources

Optimal Control of Diffusion Coefficients via Decoupling Fields [PDF]

SIAM Journal on Control and Optimization, 2018
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Ankirchner, Stefan, Fromm, Alexander
openaire   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Stack-run adaptive wavelet image compression [PDF]

, 2003
We report on the development of an adaptive wavelet image coder based on stack-run representation of the quantized coefficients. The coder works by selecting an optimal wavelet packet basis for the given image and encoding the quantization indices for ...
Awan, A. Majid, Husain, S. Afaq, Rajpoot, Nasir M. (Nasir Mahmood)   +2 more
core  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Conditional Optimal Sets and the Quantization Coefficients for Some Uniform Distributions

Mathematics
Bucklew and Wise (1982) showed that the quantization dimension of an absolutely continuous probability measure on a given Euclidean space is constant and equals the Euclidean dimension of the space, and the quantization coefficient exists as a finite ...
Evans Nyanney, Megha Pandey, Mrinal Kanti Roychowdhury   +2 more
doaj   +1 more source

A BETA‐OPTIMAL TEST OF THE EQUICORRELATION COEFFICIENT [PDF]

Australian Journal of Statistics, 1990
SummaryThis paper considers the problem of testing for nonzero values of the equicorrelation coefficient of a standard symmetric multivariate normal distribution. Recently, SenGupta (1987) proposed a locally best test. We construct a beta‐optimal test and present selected one and five percent critical values. An empirical power comparison of SenGupta's
Bhatti, Muhammad I., King, Maxwell L.
openaire   +2 more sources