Results 41 to 50 of about 19,271,700 (291)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
IEEE Access, 2020 In this study, an adaptive online data-driven tracking controller for a highly flexible aircraft (HFA) was developed. This control design innovatively combines integral reinforcement learning (IRL) and the optimal control theory to ensure asymptotic ...
Chi Peng, Jianjun Ma
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Introduction to optimal control theory
, 2002 These are lecture notes of the introductory course in Optimal Control theory treated from the geometric point of view. Optimal Control Problem is reduced to the study of controls (and corresponding trajectories) leading to the boundary of attainable sets.
AGRACHEV, A.
core +1 more source
Noosphere as Optimal Control. Part 1. Control Theory, Geosphere and Biosphere [PDF]
Философия и космология, 2017 The conceptual system developed in optimal control theory for technical purposes is used as a philosophical instrument applied to cyclic information processes, which are expected to be the basis of noosphere.
Boris Balter, Marina Faminskaya
doaj
Optimal navigation of microswimmers in complex and noisy environments
New Journal of Physics, 2022 We design new navigation strategies for travel time optimization of microscopic self-propelled particles in complex and noisy environments. In contrast to strategies relying on the results of optimal control theory or machine learning approaches ...
Lorenzo Piro +2 more
doaj +1 more source
Optimal-control theory of harmonic generation [PDF]
Physical Review A, 2012 31 ...
Schaefer, Ido, Kosloff, Ronnie
openaire +2 more sources
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Optimal and sub-optimal control in Dengue epidemics
, 2001 This work concerns the application of the optimal control theory to Dengue epidemics. The dynamics of this insect-borne disease is modelled as a set of non-linear ordinary differential equations including the effect of educational campaigns organized to ...
Yoneyama, T., Caetano, MAL
core +1 more source
An Optimal Control Approach for the Treatment of Solid Tumors with Angiogenesis Inhibitors
Mathematics, 2017 Cancer is a disease of unregulated cell growth that is estimated to kill over 600,000 people in the United States in 2017 according to the National Institute of Health.
Adam E. Glick, Antonio Mastroberardino
doaj +1 more source