Results 61 to 70 of about 19,271,700 (291)

Collision-Free Multi-UAV Optimal Path Planning and Cooperative Control for Tactical Applications [PDF]

open access: yes, 2008
AIAA Guidance, Navigation and Control Conference and Exhibit 18 - 21 August 2008, Honolulu, HawaiiStemming from previous work that addressed the optimal path planning of an unmanned aerial vehicle (UAV) in obstacle-rich environments, this paper ...
Kevin Bollino   +3 more
core   +1 more source

Nonlinear Stochastic Control and Information Theoretic Dualities: Connections, Interdependencies and Thermodynamic Interpretations

open access: yesEntropy, 2015
In this paper, we present connections between recent developments on the linearly-solvable stochastic optimal control framework with early work in control theory based on the fundamental dualities between free energy and relative entropy. We extend these
Evangelos A. Theodorou
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Controllability and Optimal Control of Microswimmers: Theory and Applications

open access: yesJournal of the Physical Society of Japan, 2023
The process of swimming at the microscopic scale is successfully described as a finite-dimensional, nonholonomic control system due to negligible inertia in the low-Reynolds number regime that holds for objects this size. The study of such systems from the point of view of mathematical control theory yields fundamental results on elementary swimmer ...
openaire   +2 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

Heteroclinic optimal control solutions for attitude motion planning [PDF]

open access: yes, 2013
An analytical attitude motion planning method is presented that exploits the heteroclinic connections of an optimal kinematic control problem. This class of motion, of hyperbolic type, supply a special case of analytically defined rotations that can be ...
Biggs, James   +7 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

An optimal gains matrix for time-delay feedback control [PDF]

open access: yes, 2009
In this paper we propose an optimal time-delayed feedback control (TDFC) for tracking unstable periodic orbits (UPOs). It is shown that TDFC will drive a trajectory onto a periodic orbit while minimising an integral of a cost function of the error in ...
Biggs, James   +6 more
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy