Results 71 to 80 of about 160,246 (263)
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Optimal Base Wavelet Selection for ECG Noise Reduction Using a Comprehensive Entropy Criterion
Entropy, 2015 The selection of an appropriate wavelet is an essential issue that should be addressed in the wavelet-based filtering of electrocardiogram (ECG) signals.
Hong He, Yonghong Tan, Yuexia Wang
doaj +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Optimized molecule detection in localization microscopy with selected false positive probability
Nature CommunicationsSingle-molecule localization microscopy (SMLM) allows imaging beyond the diffraction limit. Detection of molecules is a crucial initial step in SMLM. False positive detections, which are not quantitatively controlled in current methods, are a source of ...
Miroslav Hekrdla +5 more
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Shape optimization of waveguide filter
JSIAM Letters, 2016 The authors consider a non-parametric shape-optimization problem for waveguides with high-pass filter that passes electric signals. The problem is solved by an iterative algorithm (using the \(H^1\) gradient method), and numerical illustrations are included.
Satake, Masayoshi, Azegami, Hideyuki
openaire +2 more sources
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Experimentally enhancing high-dimensional subchannel discrimination via optimal local filtering
Physical Review ResearchThe subchannel discrimination task involves distinguishing between different branches of a quantum evolution. The guessing probability of this task can be enhanced using quantum resources such as entanglement and steerability.
Yen-An Shih +7 more
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OPTIMAL ESTIMATES OF THE IMPURITY CONCENTRATION AT BASE KALMAN FILTERING
Современная наука и инновации, 2022 The aim of study was to obtain an optimal estimate of the vector of concentration of pollutants in the atmospheric boundary layer using Kalman-Bucy.
Nataliya I. Bityutskaya +1 more
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