Results 51 to 60 of about 774,682 (254)

Variational Methods for Biomolecular Modeling

open access: yes, 2016
Structure, function and dynamics of many biomolecular systems can be characterized by the energetic variational principle and the corresponding systems of partial differential equations (PDEs).
A Ivankin   +114 more
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

A Study of Optimizing Search Engine Results Through User Interaction

open access: yesIEEE Access, 2020
In this paper, we propose a method for optimizing search engine results based on user interaction. This method generates different search results mainly through the user's operation on different search topics.
Lin-Chih Chen
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Optimal Path Choice in Railway Passenger Travel Network Based on Residual Train Capacity

open access: yesThe Scientific World Journal, 2014
Passenger’s optimal path choice is one of the prominent research topics in the field of railway passenger transport organization. More and more different train types are available, increasing path choices from departure to destination for travelers are ...
Fei Dou   +4 more
doaj   +1 more source

Recurrent urinary tract infections: evidence base and debatable issues in non-antibacterial prevention

open access: yesPočki, 2020
Recurrent urinary tract infection (UTI) is a highly prevalent, costly, and burdensome condition affecting women of all ages, races, and ethnicities without regard for socioeconomic status, or educational level.
S.O. Vozianov   +5 more
doaj   +1 more source

Investigating the optimal number of topics by advanced text-mining techniques: Sustainable energy research

open access: yesEngineering Applications of Artificial Intelligence
In recent years, there has been a growing interest in analyzing text data from different scientific fields. The significant advancement of Artificial Intelligence in Natural Language Processing enables a systematic categorization of the wealth of scientific papers into fundamental thematic clusters.
Amer Farea   +3 more
openaire   +2 more sources

Antitrust perspectives for durable-goods markets [PDF]

open access: yes, 2004
Markets for durable goods constitute an important part of the economy. In this paper I first briefly review the microeconomic theory literature on durable-goods markets, focusing mostly on the last ten years.
Waldman, Michael
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

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