Results 31 to 40 of about 8,067,351 (289)

Optimal Termination Protocols for Network Partitioning [PDF]

, 1986
We address the problem of maintaining the distributed database consistency in presence of failures while maximizing the database availability. Network partitioning is a failure which partitions the distributed system into a number of parts, no part being
Chin, Francis, Ramarao, KVS
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Tree biomass allocation is governed by allometry but modulated by optimization

Forest Ecosystems
Understanding the patterns and drivers of biomass allocation among organs at a broad scale is crucial for predicting the responses of plant growth and carbon sequestration to environmental change.
Man Hu, Hang Shi, Rui He, Nana Wang, Yuzhen Han, Haishan Dang, Quanfa Zhang   +6 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Book Reviews

Austrian Journal of Statistics, 2016
Monte Carlo Methods in Bayesian Computation. (M.-H. Chen, J.G. Ibrahim) Stat Labs, Mathematical Statistics Through Applications. (D. Nolan, T. Speed) Deskriptive Statistik. Eine Einführung mit SPSS für Windows mit Übungsaufgaben und Lösungen.
Sylvia Frühwirth-Schnatter, Werner G. Müller, Christine Duller, Immanuel M. Bomze, Michael G. Schimek, Wilfried Grossmann, Ernst Stadlober, Wolfgang Janko, Walter Böhm, Norbert Kusolitsch, Dietmar Trummer, Reinhard Viertl   +11 more
doaj   +1 more source

A Comparison of Cost Partitioning Algorithms for Optimal Classical Planning [PDF]

, 2017
Cost partitioning is a general and principled approach for constructing additive admissible heuristics for state-space search. Cost partitioning approaches for optimal classical planning include optimal cost partitioning, uniform cost partitioning, zero ...
Keller, Thomas, Seipp, Jendrik, Helmert, Malte   +2 more
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Arbuscular Mycorrhizal Symbiosis Imposes a Net Carbon Cost on Maize Under Phosphorus-Sufficient Conditions and Alters Nutrient-Dependent Scaling Trajectories

Plants
The impact of arbuscular mycorrhiza fungi (AMF) on root–shoot scaling strategies under zinc and phosphorus deficiency remains poorly understood in maize.
Luqman Dau, Arunee Wongkaew, Wannasiri Wannarat, Worachart Wisawapipat, Kreingkrai Nonkum, Orawan Kumdee, Sirilak Kaewsuralikhit, Sutkhet Nakasathien   +7 more
doaj   +1 more source

Transport-Optimal Partitioning of a Region

, 2022
This paper deals with a problem of inhabited region partitioning. The partitioning is performed when a public administration system is changed. Location of subregion centres is usually connected with the partitioning.
Jaroslav Janacek
core   +1 more source