Results 91 to 100 of about 3,761,593 (295)
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
A Control-Oriented Approach to Optimal Sensor Placement
SIAM/ASA Journal on Uncertainty QuantificationWe propose a control-oriented optimal experimental design (cOED) approach for linear PDE-constrained Bayesian inverse problems. In particular, we consider optimal control problems with uncertain parameters that need to be estimated by solving an inverse problem, which in turn requires measurement data.
Madhusudan Madhavan +4 more
openaire +3 more sources
Optimal Sensor Placement and Enhanced Sparsity for Classification
CoRR, 2013 13 pages, 11 ...
Bingni W. Brunton +3 more
openaire +2 more sources
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Approximate Optimal Deployment of Barrier Coverage on Heterogeneous Bistatic Radar Sensors
Sensors, 2019 Heterogeneous Bistatic Radars (BR) have different sensing ranges and couplings of sensing regions, which provide more flexible coverage for the boundary at complex terrain such as across rivers and valleys.
Xianghua Xu +3 more
doaj +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Optimal sensor placement for fixture fault diagnosis using Bayesian network
, 2011 PurposeFixture failures are the main cause of the dimensional variation in the assembly process. The purpose of this paper is to focus on the optimal sensor placement of compliant sheet metal parts for the fixture fault diagnosis.Design/methodology ...
Kuigang Yu +4 more
core +1 more source
Sensors, 2018 This paper investigates the problem of an optimal sensor placement for better shape deformation sensing of a new antenna structure with embedded or attached Fiber Bragg grating (FBG) strain sensors.
Jinzhu Zhou +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
A utility-based adaptive sensing and multi-hop communication protocol for wireless sensor networks
, 2000 This article reports on the development of a utility-based mechanism for managing sensing and communication in cooperative multisensor networks. The specific application on which we illustrate our mechanism is that of GlacsWeb.
Rajdeep K. Dash +11 more
core +1 more source