Results 101 to 110 of about 482,042 (298)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Evaluation of performance and statistical analysis of rigid pavement incorporating recycled aggregate concrete through the BBD methodology

Materials Research Express
The incorporation of recycled concrete aggregate (RCA) in the construction of rigid pavements has attracted considerable interest due to its environmental and economic benefits.
Karuppasamy S, Ganapathi Malarvizhi
doaj   +1 more source

Optimized Floating Offshore Wind Turbine Substructure Design Trends for 10–30 MW Turbines in Low-, Medium-, and High-Severity Wave Environments

Designs
Floating offshore wind is a promising renewable energy source, as 60% of the wind resources globally are found at depths requiring floating technologies, it minimizes construction at sea, and provides opportunities for industrialization given a lower ...
Joseph Habib Dagher, Andrew J. Goupee, Anthony M. Viselli   +2 more
doaj   +1 more source

Comparison of Box–Behnken, Central Composite, and D-Optimal Designs for Optimization of Phthalocyanine Dye Removal Using Magnetic Nanoparticles Iron Oxide Modified by Polyaspartic Acid [PDF]

شیمی کاربردی روز
In this study, the performance of the Box–Behnken, central composite and D-optimal designs (BBD, CCD or DOD, respectively) were compared for the use in modeling and optimizing the new study of the removal of phthalocyanine dye using magnetic ...
Javad Zolgharnein, Shahab Feshki, Saeideh Dermanaki Farahani   +2 more
doaj   +1 more source

Experimental Design for Sensitivity Analysis, Optimization and Validation of Simulation Models [PDF]

This chapter gives a survey on the use of statistical designs for what-if analysis in simula- tion, including sensitivity analysis, optimization, and validation/verification. Sensitivity analysis is divided into two phases.
Kleijnen, J.P.C.
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Sample size estimation and power analysis for clinical research studies

Journal of Human Reproductive Sciences, 2012
Determining the optimal sample size for a study assures an adequate power to detect statistical significance. Hence, it is a critical step in the design of a planned research protocol.
K P Suresh, S Chandrashekara
doaj   +1 more source

Bias and Efficiency of Uniform Bid Design in Contingent Valuation [PDF]

While contingent valuation (CV) methods have experienced growing popularity for estimating the willingness to pay for nonmarket goods and services, optimal bid designs for CV that provide guidance in bid point placement often render themselves ...
Kim, Sooil
core   +1 more source

Sliced rotated sphere packing designs

, 2017
Space-filling designs are popular choices for computer experiments. A sliced design is a design that can be partitioned into several subdesigns. We propose a new type of sliced space-filling design called sliced rotated sphere packing designs. Their full
He, Xu
core   +2 more sources

Design of economically and statistically optimal sampling plans

Hacettepe Journal of Mathematics and Statistics, 2016
This paper attempts to develop four types of acceptance sampling plans under the objectives of minimizing the total loss to the producer and consumer and maximizing the rate of approaching to the ideal operat ing characteristic (OC) curve when the quality characteristic follows a normal distribution and has lower specication limit.
NEZHAD, Mohammad Saber Fallah, SAREDORAHİ, Faeze Zahmatkesh, OWLİA, Mohammad Saleh, ZAD, Mohammad Ali Vahdat   +3 more
openaire   +2 more sources