Results 81 to 90 of about 118,549 (265)
DesignsFloating offshore wind is a promising renewable energy source, as 60% of the wind resources globally are found at depths requiring floating technologies, it minimizes construction at sea, and provides opportunities for industrialization given a lower ...
Joseph Habib Dagher +2 more
doaj +1 more source
Designing the statistically optimal drug for cancer therapy
, 2013 16 pages, 8 ...
Lawlor, Patrick N. +5 more
openaire +2 more sources
Design of economically and statistically optimal sampling plans
Hacettepe Journal of Mathematics and Statistics, 2016 This paper attempts to develop four types of acceptance sampling plans under the objectives of minimizing the total loss to the producer and consumer and maximizing the rate of approaching to the ideal operat ing characteristic (OC) curve when the quality characteristic follows a normal distribution and has lower specication limit.
NEZHAD, Mohammad Saber Fallah +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Comparison of Box–Behnken, Central Composite, and D-Optimal Designs for Optimization of Phthalocyanine Dye Removal Using Magnetic Nanoparticles Iron Oxide Modified by Polyaspartic Acid [PDF]
شیمی کاربردی روزIn this study, the performance of the Box–Behnken, central composite and D-optimal designs (BBD, CCD or DOD, respectively) were compared for the use in modeling and optimizing the new study of the removal of phthalocyanine dye using magnetic ...
Javad Zolgharnein +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
A comparative study of some exact designs for estimating the variance components
Kuwait Journal of ScienceThis study aims to investigate and compare several experimental designs for the efficient estimation of variance components. Some N-observation discrete/exact designs are to be considered for random effects models.
Zamzam Atash +2 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source