Results 21 to 30 of about 129,671 (267)
Optimising trial designs to identify appropriate antibiotic treatment durations
BMC Medicine, 2019 Background For many infectious conditions, the optimal antibiotic course length remains unclear. The estimation of course length must consider the important trade-off between maximising short- and long-term efficacy and minimising antibiotic resistance ...
Koen B. Pouwels +6 more
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An Overview of Adaptive Designs and Some of Their Challenges, Benefits, and Innovative Applications
Journal of Medical Internet Research, 2023 Adaptive designs are increasingly developed and used to improve all phases of clinical trials and in biomedical studies in various ways to address different statistical issues.
Hongjian Zhu, Weng Kee Wong
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Statistical Design and Optimization of Sustained Release Formulations of Pravastatin
Turkish Journal of Pharmaceutical Sciences, 2020 The objective of the current study was to formulate a sustained release (SR) formulation for pravastatin. Pravastatin is a lipid lowering, biopharmaceutical classification class-III agent.SR tablets of pravastatin were prepared using variable amounts of hydroxy methyl propyl cellulose (HPMC) K4M and sodium carboxy methyl cellulose in various ...
Raghavendra Kumar GUNDA +1 more
openaire +2 more sources
Zaštita Materijala, 2019 The present study compares the performances of the regression models developed by the response surface methodology combined with the full factorial, Box-Behnken or face central composite designs applied for the ultrasound-assisted KOH-catalyzed ...
Vlada B. Veljković +2 more
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CaTchDes: MATLAB codes for Caratheodory–Tchakaloff Near-Optimal Regression Designs
SoftwareX, 2019 We provide a MATLAB package for the computation of near-optimal sampling sets and weights (designs) for nth degree polynomial regression on discretizations of planar, surface and solid domains.
Len Bos, Marco Vianello
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Optimal designs of the median run length based double sampling X chart for minimizing the average sample size. [PDF]
PLoS ONE, 2013 Designs of the double sampling (DS) X chart are traditionally based on the average run length (ARL) criterion. However, the shape of the run length distribution changes with the process mean shifts, ranging from highly skewed when the process is in ...
Wei Lin Teoh +2 more
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Chemical Engineering Transactions, 2017 This paper analyzes the handling of hazardous chemicals in port and the management of operating them, optimizes the operation of goods yard gate of port, builds the mathematical model of yard gate and gets the optimal operation scheme of gate system by ...
Yezhu Cui, Yongjin Xie
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Designs for the simultaneous inference of concentration–response curves
BMC Bioinformatics, 2023 Background An important problem in toxicology in the context of gene expression data is the simultaneous inference of a large number of concentration–response relationships.
Leonie Schürmeyer +2 more
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Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine +17 more
wiley +1 more source
SSNdesign-An R package for pseudo-Bayesian optimal and adaptive sampling designs on stream networks.
PLoS ONE, 2020 Streams and rivers are biodiverse and provide valuable ecosystem services. Maintaining these ecosystems is an important task, so organisations often monitor the status and trends in stream condition and biodiversity using field sampling and, more ...
Alan R Pearse +6 more
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