Results 101 to 110 of about 78,187 (304)

An optimal stopping problem in a diffusion-type model with delay [PDF]

open access: yes
We present an explicit solution to an optimal stopping problem in a model described by a stochastic delay differential equation with an exponential delay measure. The method of proof is based on reducing the initial problem to a free-boundary problem and
Pavel V. Gapeev, Markus Reiß
core  

Optimal Consumption and Investment Problem with Consumption Ratcheting in Luxury Goods

open access: yesMathematics
This paper investigates an infinite-horizon optimal consumption and investment problem for an agent who consumes two types of goods: necessities and luxuries.
Geonwoo Kim, Junkee Jeon
doaj   +1 more source

Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce   +72 more
wiley   +1 more source

Optimal Stopping with Dynamic Variational Preferences [PDF]

open access: yes
We consider optimal stopping problems in uncertain environments for an agent assessing utility by virtue of dynamic variational preferences or, equivalently, assessing risk by dynamic convex risk measures.
Daniel Engelage
core  

Optimal Stopping for Partial Sums

open access: yesThe Annals of Mathematical Statistics, 1972
We determine $\sup E\lbrack r(S_T)\rbrack$, where $S_n$ is a sequence of partial sums of independent identically distributed random variables, for two reward functions: $r(x) = x^+$ and $r(x) = (e^x - 1)^+$. The supremum is taken over all stop rules $T$. We give conditions under which the optimal expected return is finite.
Darling, D. A.   +2 more
openaire   +3 more sources

GAD65 Antibody ELISA With Extended Reportable Range: Validation and Guidance for Neurological Practice

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon   +11 more
wiley   +1 more source

A Cache Placement Strategy with Energy Consumption Optimization in Information-Centric Networking

open access: yesFuture Internet, 2019
With the rapid development of cloud computing, big data, and Internet of Things, Information-Centric Networking (ICN) has become a novel hotspot in the field of future Internet architecture, and new problems have appeared. In particular, more researchers
Xin Zheng, Gaocai Wang, Qifei Zhao
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

Discounted Optimal Stopping for Maxima in Diffusion Models with Finite Horizon [PDF]

open access: yes
We present a solution to some discounted optimal stopping problem for the maximum of a geometric Brownian motion on a finite time interval. The method of proof is based on reducing the initial optimal stopping problem with the continuation region ...
Pavel V. Gapeev
core  

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