Results 91 to 100 of about 344,723 (279)
Approximation of optimal stopping problems
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Kühne, Robert, Rüschendorf, Ludger
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Movement Disorders in Aicardi–Goutières Syndrome and Response to Immunomodulation
ABSTRACT This study characterizes movement disorders and treatment responses in seven children with Aicardi–Goutières syndrome (AGS). We retrospectively evaluated motor phenotypes, neuroimaging, and interferon signatures in patients treated with baricitinib or anifrolumab. Spasticity affected all patients, while dystonia was present in 4/7.
Enrique Gonzalez Saez‐Diez +10 more
wiley +1 more source
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi +5 more
wiley +1 more source
Optimal Consumption and Investment Problem with Consumption Ratcheting in Luxury Goods
This paper investigates an infinite-horizon optimal consumption and investment problem for an agent who consumes two types of goods: necessities and luxuries.
Geonwoo Kim, Junkee Jeon
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Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension phase).
Fabrizio De Benedetti +19 more
wiley +1 more source
An urn contains $N$ objects, labelled with the integers $1, \cdots, N$. One object is removed at a time, without replacement. If after $n$ draws the largest number which has been observed is $m_n$, and the process is terminated, we receive a payoff $f(n, m_n)$. For payoff functions $f$ in a certain class, the optimal time to stop is with draw $$\tau_f =
Chen, Wen-chen, Starr, Norman
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Objective A patient‐centered approach for chronic disease management, including systemic lupus erythematosus (SLE), aligns treatment with patients’ values and preferences, leading to improved outcomes. This paper summarizes how patient experiences, perspectives, and priorities informed the American College of Rheumatology (ACR) 2024 Lupus Nephritis (LN)
Shivani Garg +20 more
wiley +1 more source
An Optimal Stopping Approach to Cell Selection in 5G Networks
Initial cell search and selection is one of the first few essential steps that a mobile device must perform to access a mobile network. The traditional maximum received power based initial cell selection may result in unbalanced loads across the cells in
Ning Wei, Guangrong Yue, Zhongpei Zhang
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Optimal Stopping Rules for Preventing Overloading of Multicomponent Systems. [PDF]
Grzybowski AZ, Domański Z, Derda T.
europepmc +1 more source
Associations of Sleep and Shift Work With Osteoarthritis Risk
Objective Daily rhythms may be critical for maintaining homeostasis of joint tissues. We aimed to investigate the relationships among circadian clock disruption, sleep, and osteoarthritis (OA) risk in humans. Methods In the UK Biobank, a prospective 500,000–person cohort, we evaluated associations among sleep duration, sleeplessness/insomnia, and shift
Elizabeth L. Yanik +5 more
wiley +1 more source

