Results 91 to 100 of about 800 (211)
Belief-Based Model of Career Dropout Under Monopsonistic Employment and Noisy Evaluation
MathematicsThis paper develops a belief-based dynamic optimisation framework to explain career continuation decisions in settings characterised by monopsonistic employment and asymmetric performance evaluation.
Iñaki Aliende +2 more
doaj +1 more source
Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach +23 more
wiley +1 more source
A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi +17 more
wiley +1 more source
A Cache Placement Strategy with Energy Consumption Optimization in Information-Centric Networking
Future Internet, 2019 With the rapid development of cloud computing, big data, and Internet of Things, Information-Centric Networking (ICN) has become a novel hotspot in the field of future Internet architecture, and new problems have appeared. In particular, more researchers
Xin Zheng, Gaocai Wang, Qifei Zhao
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To describe long‐term outcomes after anti‐CD20 discontinuation in selected patients with secondary progressive multiple sclerosis (SPMS) who remained without subsequent disease‐modifying therapy (DMT). Methods We retrospectively analyzed data from four centers in Austria and Switzerland.
Ferdinand Otto +12 more
wiley +1 more source
Optimal Stopping with Information Constraint [PDF]
Applied Mathematics & Optimization, 2012 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +3 more sources
Augmenting and Assaying Nav1.1 Protein Quantity for Dravet Syndrome Therapy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Dravet Syndrome (DS) is a developmental and epileptic encephalopathy predominantly caused by heterozygous loss‐of‐function variants in SCN1A, which encodes Nav1.1. Conserved upstream open reading frames (uORFs) in SCN1A were validated to regulate translation in reporter assays, demonstrating the therapeutic viability of increasing Nav1.1 from ...
Aiswarya Saravanan +7 more
wiley +1 more source
Optimal Stopping in a Markov Process
The Annals of Mathematical Statistics, 1968 Let $X = (X_t, \mathbf{F}_t, P^x)_{t\geqq0}$ be a Markov process where $(X_t; t \geqq 0)$ is the trajectory or sample path, $\mathbf{F}_t$ is the definitive $\sigma$-algebra of events generated by $(X_s; 0 \leqq s \leqq t)$, and $P^x$ is the probability distribution on sample paths corresponding to an initial state $x$.
openaire +2 more sources
Arthritis Care &Research, EarlyView.Objective This study aimed to describe real‐world trends in preconception and prenatal use of antirheumatic drugs among pregnant individuals with rheumatic diseases in Ontario, Canada. Methods We conducted a time‐series analysis using repeated cross‐sectional data to examine annual patterns of disease‐modifying antirheumatic drug (DMARD) use among ...
Shenthuraan Tharmarajah +6 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective JAK inhibitors (JAKi) have shown promising effects in early‐phase studies of systemic sclerosis (SSc). We aimed to assess the safety and explore the effectiveness of JAKi compared to conventional immunosuppressants in SSc. Methods A longitudinal retrospective study of the European Scleroderma Trials and Research Group (EUSTAR) cohort was ...
Stefano Di Donato +27 more
wiley +1 more source