Results 81 to 90 of about 292,252 (254)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Manufacture of IRDye800CW-coupled Fe₃O₄ nanoparticles and their applications in cell labeling and in vivo imaging

Journal of Nanobiotechnology, 2010
Background In recent years, near-infrared fluorescence (NIRF)-labeled iron nanoparticles have been synthesized and applied in a number of applications, including the labeling of human cells for monitoring the engraftment process, imaging tumors ...
Chen Zhongping, Liu Yingxun, Hou Yong, Gu Ning, Wang Jinke   +4 more
doaj   +1 more source

A Multiple Hypothesis Testing Approach to Low-Complexity Subspace Unmixing [PDF]

, 2016
Subspace-based signal processing traditionally focuses on problems involving a few subspaces. Recently, a number of problems in different application areas have emerged that involve a significantly larger number of subspaces relative to the ambient ...
Bajwa, Waheed U., Mixon, Dustin G.
core  

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Morphological, lytic, and genetic characteristics of three Brucella phages isolated from Inner Mongolia Autonomous Region

Frontiers in Microbiology
This study comprehensively examined three Brucella phages (A1, NMY-1, and NMY-2) isolated from Inner Mongolia Autonomous Region. Electron microscopy classified them as short-tailed phages.
Yu Zhang, Yu Zhang, Dongri Piao, Qingqing Xu, Yu Fan, Hongyan Zhao, Kun Li, Guozhong Tian, Kuo Han, Hai Jiang   +9 more
doaj   +1 more source

Sexual selection in the Swallow Hirundo rustica - A review [PDF]

, 2005
Darwinian theory of sexual selection and its development up to the present state of knowledge are sketched. The most important results of empirical studies on sexual selection in the Swallow Hirundo rustica are reviewed.
Bańbura, Jerzy
core  

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

FEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman, Jessica Haines, Connie Pritchard, Stephen Rutherford, Nigel Francis   +4 more
wiley   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Machine learning model for diagnosing salivary gland adenoid cystic carcinoma based on clinical and ultrasound features

Insights into Imaging
Objective To develop and validate machine learning (ML) models for diagnosing salivary gland adenoid cystic carcinoma (ACC) in the salivary glands based on clinical and ultrasound features.
Huan-Zhong Su, Zhi-Yong Li, Long-Cheng Hong, Yu-Hui Wu, Feng Zhang, Zuo-Bing Zhang, Xiao-Dong Zhang   +6 more
doaj   +1 more source

Optimized Selective Harmonic Elimination in CHB-MLI Using Red-Tailed Hawk Algorithm for Unequal DC Sources

International Journal of Robotics and Control Systems
The study develops an optimized SHE procedure to regulate a CHB-MLI powered by PV modules which use unequal DC sources. The main goal involves finding suitable switching angles that produce minimal low-order harmonics during steady output voltage operation under variable input scenarios.
Elaf Hamzah Yahia, Hasan Salman Hamad, Shouket A. Ahmed, Taha Abdulsalam Almalaisi, Hasan S. Majdi, Omer K. Ahmed, Nitin Solke, Ravi Sekhar   +7 more
openaire   +1 more source