Results 91 to 100 of about 1,375,989 (278)
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Meteorological ApplicationsAn optimal transport (OT) problem seeks to find the cheapest mapping between two distributions with equal total density, given the cost of transporting density from one place to another.
Jacob J. M. Francis +2 more
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
BioengineeringModeling drug-induced transcriptional responses at the single-cell level is essential for advancing human healthcare, particularly in understanding disease mechanisms, assessing therapeutic efficacy, and anticipating adverse effects.
Yuchen Wang +4 more
doaj +1 more source
Grand-Canonical Optimal Transport
Archive for Rational Mechanics and AnalysisWe study a generalization of the multi-marginal optimal transport problem, which has no fixed number of marginals $N$ and is inspired of statistical mechanics. It consists in optimizing a linear combination of the costs for all the possible $N$'s, while fixing a certain linear combination of the corresponding marginals.
Simone Di Marino +2 more
openaire +4 more sources
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
A strategy for non-strictly convex transport costs and the example of ||x-y||p in R2
, 2009 This paper deals with the existence of optimal transport maps for some optimal transport problems with a convex but non strictly convex cost. We give a decomposition strategy to address this issue. As part of our strategy, we have to treat some transport
Carlier, Guillaume +2 more
core +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Long-Scale Ollivier Ricci Curvature of Graphs
Analysis and Geometry in Metric Spaces, 2019 We study the long-scale Ollivier Ricci curvature of graphs as a function of the chosen idleness. Similarly to the previous work on the short-scale case, we show that this idleness function is concave and piecewise linear with at most 3 linear parts.
Cushing D., Kamtue S.
doaj +1 more source
Simple Unbalanced Optimal Transport
International Mathematics Research NoticesAbstract We introduce and study a simple model capturing the main features of unbalanced optimal transport. It is based on equipping the conical extension of the group of all diffeomorphisms with a natural metric, which allows a Riemannian submersion to the space of volume forms of arbitrary total mass. We describe its finite-dimensional
Khesin, Boris, Modin, Klas, Volk, Luke
openaire +2 more sources