Results 61 to 70 of about 1,379,735 (279)

Measurement Uncertainty for Finite Quantum Observables

Mathematics, 2016
Measurement uncertainty relations are lower bounds on the errors of any approximate joint measurement of two or more quantum observables. The aim of this paper is to provide methods to compute optimal bounds of this type. The basic method is semidefinite
René Schwonnek, David Reeb, Reinhard F. Werner   +2 more
doaj   +1 more source

Prohibiting isolated singularities in optimal transport [PDF]

, 2014
We give natural topological conditions on the support of the target measure under which solutions to the optimal transport problem with cost function satisfying the (weak) Ma, Trudinger, and Wang condition cannot have any isolated singular points.Comment:
Kim, Young-Heon, Kitagawa, Jun
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

A Gibbs Posterior Framework for Fair Clustering

Entropy
The rise of machine learning-driven decision-making has sparked a growing emphasis on algorithmic fairness. Within the realm of clustering, the notion of balance is utilized as a criterion for attaining fairness, which characterizes a clustering ...
Abhisek Chakraborty, Anirban Bhattacharya, Debdeep Pati   +2 more
doaj   +1 more source

Optimal pits and optimal transportation [PDF]

ESAIM: Mathematical Modelling and Numerical Analysis, 2015
In open pit mining, one must dig a pit, that is, excavate the upper layers of ground before reaching the ore. The walls of the pit must satisfy some geomechanical constraints, in order not to collapse. The question then arises how to mine the ore optimally, that is, how to find the optimal pit.
Ekeland, Ivar, Queyranne, Maurice
openaire   +3 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Regularized Discrete Optimal Transport for Class-Imbalanced Classifications

Mathematics
Imbalanced class data are commonly observed in pattern analysis, machine learning, and various real-world applications. Conventional approaches often resort to resampling techniques in order to address the imbalance, which inevitably alter the original ...
Jiqiang Chen, Jie Wan, Litao Ma
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Weakly Noncollapsed RCD Spaces with Upper Curvature Bounds

Analysis and Geometry in Metric Spaces, 2019
We show that if a CD(K, n) space (X, d, f ℋn) with n ≥ 2 has curvature bounded above by κ in the sense of Alexandrov then f is constant.
Kapovitch Vitali, Ketterer Christian
doaj   +1 more source