Results 31 to 40 of about 239,850 (285)

Optimal boundary control of a viscous Cahn-Hilliard system with dynamic boundary condition and double obstacle potentials [PDF]

open access: yes, 2014
In this paper, we investigate optimal boundary control problems for Cahn-Hilliard variational inequalities with a dynamic boundary condition involving double obstacle potentials and the Laplace-Beltrami operator.
Colli, Pierluigi   +3 more
core   +3 more sources

Second-Order Optimality Conditions in Cone-Constrained Vector Optimization with Arbitrary Nondifferentiable Functions

open access: yes, 2014
In this paper, we introduce a new second-order directional derivative and a second-order subdifferential of Hadamard type for an arbitrary nondifferentiable function.
Ivanov, Vsevolod I.
core   +1 more source

Optimal Control for k × k Cooperative Fractional Systems

open access: yesFractal and Fractional, 2022
This paper discusses the optimal control issue for elliptic k×k cooperative fractional systems. The fractional operators are proposed in the Laplace sense.
Hassan M. Serag   +3 more
doaj   +1 more source

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Optimality conditions for strict minimizers of higher-order in semi-infinite multi-objective optimization

open access: yesJournal of Inequalities and Applications, 2016
This paper is devoted to the study of optimality conditions for strict minimizers of higher-order for a non-smooth semi-infinite multi-objective optimization problem.
Guolin Yu
doaj   +1 more source

Quasi Efficient Solutions and Duality Results in a Multiobjective Optimization Problem with Mixed Constraints via Tangential Subdifferentials

open access: yesMathematics, 2022
We take up a nonsmooth multiobjective optimization problem with tangentially convex objective and constraint functions. In employing a suitable constraint qualification, we formulate both necessary and sufficient optimality conditions for (local) quasi ...
Mohsine Jennane   +3 more
doaj   +1 more source

Asymptotically optimal load balancing in large-scale heterogeneous systems with multiple dispatchers [PDF]

open access: yes, 2020
We consider the load balancing problem in large-scale heterogeneous systems with multiple dispatchers. We introduce a general framework called Local-Estimation-Driven (LED).
Shroff, Ness   +2 more
core   +2 more sources

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle   +5 more
wiley   +1 more source

On the Minimization of Convex Functionals of Probability Distributions Under Band Constraints

open access: yes, 2018
The problem of minimizing convex functionals of probability distributions is solved under the assumption that the density of every distribution is bounded from above and below.
Fauss, Michael, Zoubir, Abdelhak M.
core   +1 more source

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