Results 41 to 50 of about 32,948 (308)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Journal of Inequalities and Applications, 2016 This paper is devoted to the study of optimality conditions for strict minimizers of higher-order for a non-smooth semi-infinite multi-objective optimization problem.
Guolin Yu
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Optimality conditions for multiobjective symmetric convex programming
Journal of Numerical Analysis and Approximation Theory, 1996 Not available.
Ştefan Ţigan
doaj +2 more sources
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Operator Methods of the Maximum Principle in Problems of Optimization of Quantum Systems
Mathematics, 2022 In the class of optimal control problems for quantum systems, operator optimality conditions for control are constructed in the form of fixed-point problems in the control space.
Alexander Buldaev, Ivan Kazmin
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Solving ill-posed bilevel programs [PDF]
, 2016 This paper deals with ill-posed bilevel programs, i.e., problems admitting multiple lower-level solutions for some upper-level parameters. Many publications have been devoted to the standard optimistic case of this problem, where the difficulty is ...
Zemkoho, Alain B., Alain B. Zemkoho
core +1 more source
On Necessary Optimality Conditions for Discrete Control Systems
Известия Иркутского государственного университета: Серия "Математика", 2020 In this article, under weakened assumptions, we study high-order necessary optimality conditions for discrete optimal control problems with the free right end of the trajectory.
M. J. Mardanov, T. K. Melikov
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
First- and second-order optimality conditions for mathematical programs with vanishing constraints [PDF]
, 2007 summary:We consider a special class of optimization problems that we call Mathematical Programs with Vanishing Constraints, MPVC for short, which serves as a unified framework for several applications in structural and topology optimization.
Hoheisel, Tim, Kanzow, Christian
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