Results 51 to 60 of about 17,832 (262)
Optimality Conditions and Duality in Nonsmooth Multiobjective Programs
Journal of Inequalities and Applications, 2010 We study nonsmooth multiobjective programming problems involving locally Lipschitz functions and support functions. Two types of Karush-Kuhn-Tucker optimality conditions with support functions are introduced.
Kim DoSang, Lee HyoJung
doaj +2 more sources
Conditional Optimal Stopping: A Time-Inconsistent Optimization [PDF]
SSRN Electronic Journal, 2019 Forthcoming in 'Annals of Applied Probability'
Nutz, Marcel, Zhang, Yuchong
openaire +3 more sources
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Global optimality conditions for mixed integer nonlinear programming problems
四川大学学报. 自然科学版, 2017 In recent years, the application of mixed integer nonlinear programming problem has been extremely active and very extensive. In this paper, some necessary conditions for a given global minimizer applied to mixed integer nonlinear programming problem ...
QUAN Jing, LI Guo-Quan
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Optimality Conditions for Preinvex Functions Using Symmetric Derivative [PDF]
Operations Research and Decisions, 2022 As a generalization of convex functions and derivatives, in this paper, the authors study the concept of a symmetric derivative for preinvex functions. Using symmetrical differentiation, they discuss an important characterization for preinvex functions ...
Sachin Rastogi +2 more
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FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Discrete Nonuniform Systems and Sufficient Conditions of Optimality
Известия Иркутского государственного университета: Серия "Математика", 2017 Nonuniform systems are the object of a deep investigation last 15–20 years. They are exemplified by the chemical processes, complicated operations in space, robot dynamics, development of organisms and biological populations.
I.V. Rasina
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