Results 61 to 70 of about 32,948 (308)
Optimality conditions for a Timoshenko beam model [PDF]
, 2022 Optimality conditions for a Timoshenko beam model are derived in the maximum principle. For this aim, existence and uniqueness of the solution to the beam system and controllability properties of the system are discussed.
Yıldırım, Kenan, Kenan Yildirim
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pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Second-order optimality conditions for bilevel programs [PDF]
, 2023 Second-order optimality conditions of the bilevel programming problems are dependent on the second-order directional derivatives of the value functions or the solution mappings of the lower level problems under some regular conditions, which can not be ...
Zhang, Liwei, Liu, Xiang, Xu, Mengwei
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Necessary and sufficient conditions for a Pareto optimal allocation in a discontinuous Gale economic model [PDF]
Opuscula Mathematica, 2014 In this paper we examine the concept of Pareto optimality in a simplified Gale economic model without assuming continuity of the utility functions. We apply some existing results on higher-order optimality conditions to get necessary and sufficient ...
Anna Michalak, Marcin Studniarski
doaj +1 more source
Conditional Optimal Stopping: A Time-Inconsistent Optimization [PDF]
SSRN Electronic Journal, 2019 Forthcoming in 'Annals of Applied Probability'
Nutz, Marcel, Zhang, Yuchong
openaire +3 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Optimality Theory and the Minimalist Program [PDF]
, 2006 In this paper I argue that an OT-approach to grammar is actually essential to minimalist investigations, because it dramatically widens the set of linguistic properties potentially reducible to interface conditions while at the same time dispensing with ...
core
Optimality Conditions and Duality in Nonsmooth Multiobjective Programs
Journal of Inequalities and Applications, 2010 We study nonsmooth multiobjective programming problems involving locally Lipschitz functions and support functions. Two types of Karush-Kuhn-Tucker optimality conditions with support functions are introduced.
Kim DoSang, Lee HyoJung
doaj +2 more sources
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Second Order Optimality Conditions in Multiobjective Programming [PDF]
, 1998 In this paper we will establish some necessary and/or sufficient optimality conditions for a vector maximization problem. These conditions are firstly stated without the use of any constraint qualifications, then the given approach allow us to introduce ...
CAMBINI, RICCARDO
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