Results 81 to 90 of about 239,850 (285)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Field- and concentration-dependent relaxation of magnetic nanoparticles and optimality conditions for magnetic fluid hyperthermia. [PDF]
Sci Rep, 2023 Ilg P, Kröger M.
europepmc +1 more source
Hodges-Lehmann Optimality for Testing Moment [PDF]
This paper studies the Hodges and Lehmann (1956) optimality of tests in a general setup. The tests are compared by the exponential rates of growth to one of the power functions evaluated at a fixed alternative while keeping the asymptotic sizes bounded ...
Ivan Canay, Taisuke Otsu
core
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Optimality Conditions and Duality in Nonsmooth Multiobjective Programs
Journal of Inequalities and Applications, 2010 We study nonsmooth multiobjective programming problems involving locally Lipschitz functions and support functions. Two types of Karush-Kuhn-Tucker optimality conditions with support functions are introduced.
Kim DoSang, Lee HyoJung
doaj +2 more sources
Unified Robust Necessary Optimality Conditions for Nonconvex Nonsmooth Uncertain Multiobjective Optimization. [PDF]
J Optim Theory Appl, 2022 Wang J, Li S, Feng M.
europepmc +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Higher-Order Optimality Conditions in Set-Valued Optimization with Respect to General Preference Mappings. [PDF]
Set Valued Var Anal, 2022 Michalak A, Studniarski M.
europepmc +1 more source
C 1,1 functions and optimality conditions [PDF]
In this work we provide a characterization of C 1,1 functions on Rn (that is, differentiable with locally Lipschitz partial derivatives) by means of second directional divided differences.
La Torre Davide, Rocca Matteo
core