Results 101 to 110 of about 7,727,198 (309)

Optimality conditions for an interval-valued vector problem

open access: yes
summary:The present article considers a nonsmooth interval-valued vector optimization problem with inequality constraints. We first figure out Fritz John and Karush-Kuhn-Tucker type necessary optimality conditions for the interval-valued problem designed
Prasad, Ashish Kumar   +2 more
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

On Generalized Constrained Optimization and Separation Theorems [PDF]

open access: yes
In this paper a generalized format for a constrained extremum problem is considered. Subsequently, the paper investigates and deepens some aspects concerning the linear separation between two sets in the Euclidean space, that are a convex cone and a ...
Letizia Pellegrini
core  

Dialectal variation in german 3-verb clusters : a surface-oriented optimality theoretic account [PDF]

open access: yes, 2004
We present data from an empirical investigation on the dialectal variation in the syntax of German 3-verb clusters, consisting of a temporal auxiliary, a modal verb, and a predicative verb. The ordering possibilities vary greatly among the dialects. Some
Schmid, Tanja   +2 more
core   +1 more source

Applications of Lyapunov Type Functions for Optimization Problems in Impulsive Control Systems

open access: yesИзвестия Иркутского государственного университета: Серия "Математика", 2015
This paper deals with an application of Lyapunov type functions for optimality conditions of impulsive processes. A impulsive optimal control problem with trajectories of bounded variation and impulsive controls (regular vector measures) is considered ...
O.N. Samsonyuk
doaj  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

On a Method for Finding Extremal Controls in Systems with Constraints

open access: yesИзвестия Иркутского государственного университета: Серия "Математика", 2019
In the class of controlled systems with constraints, the conditions for improving and optimality of control are constructed and analyzed in the form of fixed point problems.
A.S. Buldaev, I. D. Burlakov
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

On constrained set-valued optimization [PDF]

open access: yes
The set-valued optimization problem minC F(x), G(x)\(-K) 6= ; is considered, where F : Rn Rm and G : Rn Rp are set-valued functions, and C Rm and K Rp are closed convex cones.
Rocca Matteo, Ginchev Ivan
core  

M-estimator, and D-optimality model construction using orthogonal forward regression

open access: yes, 2005
This correspondence introduces a new orthogonal forward regression (OFR) model identification algorithm using D-optimality for model structure selection and is based on an M-estimators of parameter estimates.
Hong, X., Chen, S.
core   +1 more source

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