, 2005 The object of the present work is the analysis of the convergence behaviour of a learning algorithm for grammars belonging to a special version -- the maximum entropy version -- of stochastic Optimality Theory.
Fischer, Markus
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Necessary Conditions for Optimality for Stochastic Evolution Equations
Abstract and Applied Analysis, 2013 This paper is concerned with providing the maximum principle for a control problem governed by a stochastic evolution system on a separable Hilbert space.
AbdulRahman Al-Hussein
doaj +1 more source
Robust Necessary Optimality Conditions for Nondifferentiable Complex Fractional Programming with Uncertain Data. [PDF]
J Optim Theory Appl, 2021 Chen J +4 more
europepmc +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
A survey on C 1,1 fuctions: theory, numerical methods and applications [PDF]
In this paper we survey some notions of generalized derivative for C 1,1 functions. Furthermore some optimality conditions and numerical methods for nonlinear minimization problems involving C1,1 data are studied.
Rocca Matteo, La Torre Davide
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Optimality Conditions for a Nonsmooth Uncertain Multiobjective Programming Problem
Complexity, 2020 This note is devoted to the investigation of optimality conditions for robust approximate quasi weak efficient solutions to a nonsmooth uncertain multiobjective programming problem (NUMP).
Wenyan Han, Guolin Yu, Tiantian Gong
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Necessary and Sufficient Conditions for Pareto Optimality in Infinite Horizon Cooperative Differential Games [PDF]
In this article we derive necessary and sufficient conditions for the existence of Pareto optimal solutions for infinite horizon cooperative differential games. We consider games defined by non autonomous and discounted autonomous systems.
Engwerda, J.C., Reddy, P.V.
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First- and second-order optimality conditions for mathematical programs with vanishing constraints [PDF]
, 2007 summary:We consider a special class of optimization problems that we call Mathematical Programs with Vanishing Constraints, MPVC for short, which serves as a unified framework for several applications in structural and topology optimization.
Hoheisel, Tim, Kanzow, Christian
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Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source