Results 41 to 50 of about 238,335 (283)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Complex Inferential Processes Are Needed for Implicature Comprehension, but Not for Implicature Production

Frontiers in Psychology, 2021
Upon hearing “Some of Michelangelo’s sculptures are in Rome,” adults can easily generate a scalar implicature and infer that the intended meaning of the utterance corresponds to “Some but not all Michelangelo’s sculptures are in Rome.” Comprehension ...
Irene Mognon, Simone A. Sprenger, Sanne J. M. Kuijper, Petra Hendriks   +3 more
doaj   +1 more source

Learning OT constraint rankings using a maximum entropy model [PDF]

, 2003
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Goldwater, Sharon, Johnson, M
core   +3 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Effect of Complexity on Speech Sound Development: Evidence From Meta-Analysis Review of Treatment-Based Studies

Frontiers in Psychology, 2021
In the current study, we aimed at understanding the effect of exposure to complex input on speech sound development, by conducting a systematic meta-analysis review of the existing treatment-based studies employing complex input in children with speech ...
Akshay R. Maggu, Akshay R. Maggu, Akshay R. Maggu, René Kager, René Kager, Carol K. S. To, Judy S. K. Kwan, Patrick C. M. Wong, Patrick C. M. Wong, Patrick C. M. Wong   +9 more
doaj   +1 more source

Backward variational approach on time scales with an action depending on the free endpoints

, 2011
We establish necessary optimality conditions for variational problems with an action depending on the free endpoints. New transversality conditions are also obtained.
Malinowska, Agnieszka B., Torres, Delfim F. M.   +1 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Glide Formation in Kalhori Dialect [PDF]

̒Ilm-i Zabān, 2014
In this paper, the aim is to analyze and describe the process of glide formation in Kurdish (Kalhori dialect) using optimality theory of concurrency approach.
Ebrahim Badakhshan, Mohammad Zamani
doaj   +1 more source

Erasable/Inerasable L1 Transfer in Interlanguage Phonology: An Optimality Theory Analysis of /aʊn/ and Sentence Stress in Chinese Learners of English

Contemporary Social Sciences, 2022
The areas affected by the L1 transfer to L2, such as phonotactics and stress, appear to have different degrees of erasability through training and practice.
Fan Yi
doaj   +1 more source

Mathematical methods of optimal control theory and their applications [PDF]

, 2011
Tato diplomová práce se zabývá problematikou spojitého optimálního řízení, což je jedna z nejvýznamnějších aplikací teorie diferenciálních rovnic. Cílem této práce bylo jak nastudování matematické teorie optimálního řízení, tak především ukázat užití ...
Felixová, Lucie
core