Results 61 to 70 of about 23,247 (311)

Optimality Theory and Prosodic Morphology [PDF]

open access: yes, 2019
A central concern of Optimality Theory from its beginnings (McCarthy & Prince 1993a, Prince & Smolensky 1993/2004) has been to provide a coherent framework for formalizing the traditional problems prosodic morphology poses for morphological analysis.
Downing, Laura J.,
core   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Phonological derivation in optimality theory [PDF]

open access: yesProceedings of the 15th conference on Computational linguistics -, 1994
Optimality Theory is a constraint-based theory of phonology which allows constraints to be violated. Consequently, implementing the theory presents problems for declarative constraint-based processing frameworks. On the basis of two regularity assumptions, that candidate sets are regular and that constraints can be modelled by transducers, this paper ...
openaire   +3 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Optimality and the Theory of Value

open access: yesJournal of Economic Theory, 1994
Let \(X_i\subset \mathbb{R}^q\) be the consumption set of the consumer \(i\) \((= 1,2,\dots, m)\). The complete and transitive preference relation \(\lesssim_i\) of the consumer \(i\) is represented by a continuous utility function \(u_i: X_i\to \mathbb{R}\). \(Y\) denotes the total production set of the economy. A pair \((x^*, p^*)\in \left(\prod^m_{i=
openaire   +1 more source

Object Agreement in Palauan: Specificity, Humanness, Economy, and Optimality [PDF]

open access: yes, 1995
Complex conditions on object agreement and preposition insertion in Palauan, conditioned by aspect, specificity, number, and humanness, are shown to follow from a modified version of Diesing's Mapping Hypothesis interacting with (ranked with respect to ...

core  

Optimality and Wh-Extraction [PDF]

open access: yes, 1995
In this paper, we propose to start addressing the issues outlined above from the perspective of Optimality Theory (OT, Prince and Smolensky, 1993) and test the hypothesis that different patterns of extractability across languages result from different ...
Raymond, William   +4 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

The Typology of Rounding Harmony: An Optimality Theoretic Approach [PDF]

open access: yes, 1995
This thesis explores the typology of rounding harmony within the framework of optimality theory. A systematic survey of the range of attested rounding harmony phenomena is presented and an analysis of this typology is proposed which invokes constraints ...
Kaun, Abigail Rhoades
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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