Results 71 to 80 of about 239,489 (284)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Hypocoristic names as the pattern of the representing the verbal protest and satisfying in Kermanshah Kurdish [PDF]
مطالعات زبانها و گویشهای غرب ایران, 2015 The current study investigates the patterns for forming hypocoristic names used to represent verbal protest and satisfaction in relation to three social factors: gender, age and context.
Bahman Haidari
doaj
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
PARETO-OPTIMALITY AND L-OPTIMAL FOR SOLVING SOME CLASSES OF OPTIMAL CONTROL PROBLEM
Финансы: теория и практика, 2017 Many practical problems of economic activities and a number of important issues of economic theory are connected to the choice of optimal solution. An adequate economic theory should reflect the process of continuous development of the economic system ...
V. V. Kiselev
doaj +1 more source
Diophantine approximation in Banach spaces [PDF]
, 2016 In this paper, we extend the theory of simultaneous Diophantine approximation to infinite dimensions. Moreover, we discuss Dirichlet-type theorems in a very general framework and define what it means for such a theorem to be optimal.
Fishman, Lior +2 more
core
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Optimality Theoretic Account of Acquisition of Consonant Clusters of English Syllables by Persian EFL Learners [PDF]
Journal of English Language Teaching and Learning, 2010 This study accounts for the acquisition of the consonant clusters of English syllable structures both in onset and coda positions by Persian EFL learners.
Ali Akbar Jabbari, Leila Arghavan
doaj
Schwa in Contemporary Standard Russian
Poljarnyj Vestnik: Norwegian Journal of Slavic Studies, 2000 This article explores a number of generalizations regarding the distribution of schwa in Russian and outlines an analysis in terms of Optimality Theory.
Tore Nesset
doaj +1 more source
On Poincare and logarithmic Sobolev inequalities for a class of singular Gibbs measures
, 2019 This note, mostly expository, is devoted to Poincar{\'e} and log-Sobolev inequalities for a class of Boltzmann-Gibbs measures with singular interaction. Such measures allow to model one-dimensional particles with confinement and singular pair interaction.
A Arnold +39 more
core +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source