Results 71 to 80 of about 11,404 (263)
A bidirectional Optimality Theoretic analysis of multiple negative indefinites in Afrikaans
Stellenbosch Papers in Linguistics, 2014 In the literature on negation, Afrikaans is generally categorised as a negative concord language. Unlike most other negative concord languages though, utterances containing multiple indefinites in the scope of negation are typically produced with a ...
Huddlestone, Kate, de Swart, Henriëtte
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Asymptotic Optimality Theory for Active Quickest Detection with Unknown PostChange Parameters. [PDF]
Seq Anal, 2023 Xu Q, Mei Y.
europepmc +1 more source
Optimization in Theory and Practice
CoRRAlgorithms for continuous optimization problems have a rich history of design and innovation over the past several decades, in which mathematical analysis of their convergence and complexity properties plays a central role. Besides their theoretical properties, optimization algorithms are interesting also for their practical usefulness as computational
openaire +2 more sources
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Coordination of plant hydraulic and photosynthetic traits: confronting optimality theory with field measurements. [PDF]
New Phytol, 2021 Xu H +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Optimality Theoretic Account of Acquisition of Consonant Clusters of English Syllables by Persian EFL Learners [PDF]
Journal of English Language Teaching and Learning, 2010 This study accounts for the acquisition of the consonant clusters of English syllable structures both in onset and coda positions by Persian EFL learners.
Ali Akbar Jabbari, Leila Arghavan
doaj
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source