Results 91 to 100 of about 23,247 (311)
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Optimality Theoretic Account of Acquisition of Consonant Clusters of English Syllables by Persian EFL Learners [PDF]
Journal of English Language Teaching and Learning, 2010 This study accounts for the acquisition of the consonant clusters of English syllable structures both in onset and coda positions by Persian EFL learners.
Ali Akbar Jabbari, Leila Arghavan
doaj
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Optimality Theory or Language in a Dodgeball Game
Rasprave Instituta za Hrvatski Jezik i Jezikoslovlje, 2014 The aim of this paper is to present Optimality theory (OT), one of the most prominent contemporary linguistic theories developed in the 1990s by two phonologists Alan Prince and Paul Smolensky (1991/1993, 2004).
Mia Batinić
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Optimal Planning Modulo Theories
, 2020 Dissertation, RWTH Aachen University, 2020; Aachen 1 Online-Ressource (96 Seiten) : Illustrationen, Diagramme (2020).
openaire +3 more sources
An Iterative Strategy for Learning Metrical Stress in Optimality Theory [PDF]
, 1996 One of the major challenges of language acquisition is the fact that the auditory signal received by a child can underdetermine the structural description of the utterance.
core +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Optimality and duality in set-valued optimization utilizing limit sets
Open Mathematics, 2018 This paper deals with optimality conditions and duality theory for vector optimization involving non-convex set-valued maps. Firstly, under the assumption of nearly cone-subconvexlike property for set-valued maps, the necessary and sufficient optimality ...
Kong Xiangyu, Zhang Yinfeng, Yu GuoLin
doaj +1 more source
Faithfulness and Reduplicative Identity [PDF]
, 1995 This paper proposes a revised view of faithfulness in Optimality Theory (Prince & Smolensky 1993), relating it to reduplicative identity (McCarthy & Prince 1993).
core +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source