Results 81 to 90 of about 676,204 (267)

Shorter Total Length of Stay After Intraperitoneal Fosfomycin, Metronidazole, and Molgramostim for Complicated Appendicitis: A Pivotal Quasi-Randomized Controlled Trial

Frontiers in Surgery, 2020
Background: We aimed to investigate the difference in the total length of hospital stay (LOS) after intraperitoneal vs. intravenous antibiotic treatment in patients with complicated appendicitis.Methods: We conducted a quasi-randomized prospective ...
Siv Fonnes, Søren Roepstorff, Barbara Juliane Holzknecht, Christoffer Skov Olesen, Joachim Hjalde Halmsted Olsen, Line Schmidt, Rasmus Alder, Sara Gamborg, Tilde Rasmussen, Magnus Arpi, Lars Nannestad Jørgensen, Jacob Rosenberg   +11 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Design of general-purpose sampling strategies for geometric shape measurement [PDF]

, 2011
Quality inspection is a preliminary step for different further analyses (process monitoring, control and optimisation) and requires one to select a measuring strategy, i.e., number and location of measurement points.
Colosimo, Bianca Maria, Gutiérrez Moya, Ester, Onieva, Luis, Semeraro, Quirico   +3 more
core   +1 more source

Development of an ethical framework for the use of social robots in the care of individuals with major neurocognitive disorders: a qualitative study

BMC Geriatrics
Background Despite the growing use of social robots in geriatric care, there is a lack of standardized ethical guidelines to inform and guide professionals in their implementation.
Caitlin Ware, Anne-Sophie Rigaud, Lauriane Blavette, Souad Damnée, Sebastien Dacunha, Hermine Lenoir, Matthieu Piccoli, Victoria Cristancho-Lacroix, Maribel Pino   +8 more
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Support Vector Machine Regression for Calibration Transfer between Electronic Noses Dedicated to Air Pollution Monitoring

Sensors, 2018
Recently, the emergence of low-cost sensors have allowed electronic noses to be considered for densifying the actual air pollution monitoring networks in urban areas.
Rachid Laref, Etienne Losson, Alexandre Sava, Maryam Siadat   +3 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Direct Step & Shoot: a New Module for Prostate Cancer IMRT [PDF]

, 2007
Aims & Objectives The aim of this treatment planning study is to compare the techniques of 3D conformal radiotherapy (3DCRT) and IMRT to determine the feasible advantages for prostate cancer patientsof using a new direct step & shoot (DSS) IMRT module.
Bogner, Ludwig, Hipp, Matthias, Treutwein, Marius   +2 more
core  

Diagnostics-linked Antimicrobial Surveillance: A Route to Patient-Centred Microbiology Diagnostics?

International Journal of Infectious Diseases
Introduction: Microbiology diagnostics are widely recognised as an important tool in the fight against antimicrobial resistance (AMR), due to their ability to provide information to clinicians to inform antimicrobial treatment.
Dr Alex Howard, Dr Charlotte Brookfield, Dr Conor Rosato, Dr Anoop Velluva, Dr Alessandro Gerada, Professor William Hope   +5 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source