Results 121 to 130 of about 5,593,327 (347)

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

open access: yesMolecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu   +3 more
wiley   +1 more source

A Survey of Methods for Gas-Lift Optimization

open access: yesModelling and Simulation in Engineering, 2012
This paper presents a survey of methods and techniques developed for the solution of the continuous gas-lift optimization problem over the last two decades. These range from isolated single-well analysis all the way to real-time multivariate optimization
Kashif Rashid   +2 more
doaj   +1 more source

Using Big Data-machine learning models for diabetes prediction and flight delays analytics

open access: yesJournal of Big Data, 2020
Introduction Nowadays large data volumes are daily generated at a high rate. Data from health system, social network, financial, government, marketing, bank transactions as well as the censors and smart devices are increasing.
Thérence Nibareke, Jalal Laassiri
doaj   +1 more source

Local Versus Global Conditions in Polynomial Optimization [PDF]

open access: yesarXiv, 2015
This paper reviews local and global optimality conditions in polynomial optimization. We summarize the relationship between them.
arxiv  

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

open access: yesMolecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran   +16 more
wiley   +1 more source

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu   +7 more
wiley   +1 more source

A New Reduction from Search SVP to Optimization SVP [PDF]

open access: yes, 2012
It is well known that search SVP is equivalent to optimization SVP. However, the former reduction from search SVP to optimization SVP by Kannan needs polynomial times calls to the oracle that solves the optimization SVP.
Hu, Gengran, Pan, Yanbin
core  

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

open access: yesMolecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy   +12 more
wiley   +1 more source

Research on OPF Control of Three-Phase Four-Wire Low-Voltage Distribution Network considering Uncertainty

open access: yesInternational Transactions on Electrical Energy Systems
As power systems become more complex and uncertain, low-voltage distribution networks face numerous challenges, including three-phase imbalances caused by asymmetrical loads and distributed energy resources.
Rui Wang   +3 more
doaj   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

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