Results 41 to 50 of about 475,413 (306)
Optimal Distributed Covering Algorithms [PDF]
Proceedings of the 2019 ACM Symposium on Principles of Distributed Computing, 2019 AbstractWe present a time-optimal deterministic distributed algorithm for approximating a minimum weight vertex cover in hypergraphs of rank f. This problem is equivalent to the Minimum Weight Set Cover problem in which the frequency of every element is bounded by f. The approximation factor of our algorithm is $$(f+\varepsilon )$$
Ben-Basat, Ran +3 more
openaire +7 more sources
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
HeliyonThis paper proposes Pomarine jaeger Optimization (PJO) algorithm, Tiger hunting Optimization (THO) Algorithm, Desert Reynard and Vixen Inspired Optimization (DRVIO) Algorithm, Lonchodidae optimization (LO) algorithm, Caracal optimization (CO) algorithm ...
Lenin Kanagasabai
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
A Brief Comparison of Particle Swarm Optimization Algorithm and Firefly Algorithm
Jurnal informatika UPGRIS, 2018 In this article, we try to present some optimization algorithms that are often used by researchers. Through the information contained in this article, the reader can know and understand the development and mechanism of optimization algorithms.
Ahmad Sanmorino
doaj +1 more source
Registration of dermatoscopic images of skin neoplasms and detection of structural differences
Системный анализ и прикладная информатика, 2023 The paper considers the application of an algorithm based on a morphological projector for determining structural differences for comparing dermoscopic images.
A. F. Smalyuk +2 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Raccoon Optimization Algorithm
IEEE Access, 2019 Population-based meta-heuristic is a high-level method intended to provide sufficient solution for problems with incomplete information among a massive volume of solutions. However, it does not guarantee to attain global optimum in a reasonable time.
Sina Zangbari Koohi +3 more
doaj +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source