Results 51 to 60 of about 600,362 (302)
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
, 2011 This article presents an algorithm for multi-objective optimization that blends together a number of heuristics. A population of agents combines heuristics that aim at exploring the search space both globally and in a neighbourhood of each agent.
Vasile, M. +3 more
core +1 more source
Orthogonal methods based ant colony search for solving continuous optimization problems [PDF]
, 2008 Research into ant colony algorithms for solving continuous optimization problems forms one of the most significant and promising areas in swarm computation.
Jun Zhang +5 more
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
, 2010 Continuous optimization is one of the areas with more activity in the field of heuristic optimization. Many algorithms have been proposed and compared on several benchmarks of functions, with different performance depending on the problems.
Antonio LaTorre +5 more
core +2 more sources
HeliyonThis paper proposes Pomarine jaeger Optimization (PJO) algorithm, Tiger hunting Optimization (THO) Algorithm, Desert Reynard and Vixen Inspired Optimization (DRVIO) Algorithm, Lonchodidae optimization (LO) algorithm, Caracal optimization (CO) algorithm ...
Lenin Kanagasabai
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Enhanced Flexible Algorithm for the Optimization of Slot Filling Factors in Electrical Machines
Energies, 2020 The continuous development in the field of industrial automation and electric mobility has led to the need for more efficient electrical machines with a high power density.
Armin Dietz +4 more
doaj +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
A Brief Comparison of Particle Swarm Optimization Algorithm and Firefly Algorithm
Jurnal informatika UPGRIS, 2018 In this article, we try to present some optimization algorithms that are often used by researchers. Through the information contained in this article, the reader can know and understand the development and mechanism of optimization algorithms.
Ahmad Sanmorino
doaj +1 more source