Results 41 to 50 of about 600,362 (302)

On the Optimization of Dijkstra’s Algorithm [PDF]

, 2011
In this paper, we propose some amendment on Dijkstras algorithm in order to optimize it by reducing the number of iterations. The main idea is to solve the problem where more than one node satisfies the condition of the second step in the traditional Dijkstras algorithm.
Seifedine Nimer Kadry, Ayman Abdallah, Chibli Joumaa   +2 more
openaire   +2 more sources

Inducing decision trees with an ant colony optimization algorithm [PDF]

, 2012
Decision trees have been widely used in data mining and machine learning as a comprehensible knowledge representation. While ant colony optimization (ACO) algorithms have been successfully applied to extract classification rules, decision tree induction ...
Otero, Fernando E.B., Johnson, Colin G., Freitas, Alex A.   +2 more
core   +1 more source

Algorithmic lifestyle optimization

Journal of the American Medical Informatics Association, 2022
Abstract Objective A hallmark of personalized medicine and nutrition is to identify effective treatment plans at the individual level. Lifestyle interventions (LIs), from diet to exercise, can have a significant effect over time, especially in the case of food intolerances and allergies. The large set
Ameen Eetemadi, Ilias Tagkopoulos
openaire   +4 more sources

Evolutionary Synthesis of HVAC System Configurations: Algorithm Development. [PDF]

, 2008
This paper describes the development of an optimization procedure for the synthesis of novel heating, ventilating, and air-conditioning (HVAC) system configurations. Novel HVAC system designs can be synthesized using model-based optimization methods. The
Angelov, Plamen, Yi Zhang (9093), Jonathan Wright, Wright, Jonathan A., Richard Buswell, Plamen Angelov, Hanby, Victor I., Victor I. Hanby (7176788), Zhang, Yi, Yi Zhang, Jonathan Wright (1257306), Plamen Angelov (5037638), Richard Buswell (1249932), Buswell, Richard A., Victor Hanby   +14 more
core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Discovering Regression Rules with Ant Colony Optimization [PDF]

, 2015
The majority of Ant Colony Optimization (ACO) algorithms for data mining have dealt with classification or clustering problems. Regression remains an unexplored research area to the best of our knowledge.
Brookhouse, James, Otero, Fernando E.B., James Brookhouse, Fernando E.B. Otero   +3 more
core   +1 more source

Registration of dermatoscopic images of skin neoplasms and detection of structural differences

Системный анализ и прикладная информатика, 2023
The paper considers the application of an algorithm based on a morphological projector for determining structural differences for comparing dermoscopic images.
A. F. Smalyuk, A. G. Zhukovets, N. M. Trizna   +2 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source