Results 61 to 70 of about 1,773,374 (329)

ALGORITHMS, LEARNING, AND OPTIMIZATION

open access: yes, 2020
This thesis covers some algorithmic aspects of online machine learning and optimization. In Chapter 1 we design algorithms with state-of-the-art regret guarantees for the problem dynamic pricing. In Chapter 2 we move on to an asynchronous online learning setting in which only some of the agents in the network are active at each time step.
openaire   +3 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Enhanced Flexible Algorithm for the Optimization of Slot Filling Factors in Electrical Machines

open access: yesEnergies, 2020
The continuous development in the field of industrial automation and electric mobility has led to the need for more efficient electrical machines with a high power density.
Armin Dietz   +4 more
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

An enhanced random early marking algorithm for Internet flow control [PDF]

open access: yes, 1999
We propose earlier an optimization based flow control for the Internet called Random Early Marking (REM). In this paper we propose and evaluate an enhancement that attempts to speed up the convergence of REM in the face of large feedback delays.
Athuraliya, Sanjeewa   +2 more
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

A modified migration model biogeography evolutionary approach for electromagnetic device multiobjective optimization [PDF]

open access: yes, 2014
Inthispaper, we present anefficient androbust algorithm for multiobjective optimization of electromagnetic devices.Therecentlydeveloped biogeography-based optimization (BBO) is modified byadapting its migration model function so as to improve its ...
Dupré, Luc   +2 more
core  

Instance-Optimal Geometric Algorithms [PDF]

open access: yesJournal of the ACM, 2009
We prove the existence of an algorithm A for computing 2D or 3D convex hulls that is optimal for every point set in the following sense: for every sequence σ of n points and for every algorithm A ′ in a certain class A ...
Peyman Afshani   +2 more
openaire   +5 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

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