Results 71 to 80 of about 1,773,374 (329)

Applications of Bee Colony Optimization [PDF]

open access: yes, 2013
Many computationally difficult problems are attacked using non-exact algorithms, such as approximation algorithms and heuristics. This thesis investigates an ex- ample of the latter, Bee Colony Optimization, on both an established optimization problem in
CHALK, AIDAN BERNARD GERARD
core  

Optimal heapsort algorithm

open access: yesTheoretical Computer Science, 1996
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Gu Xunrang, Zhu Yuzhang
openaire   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Experimental study on diesel engine exhaust gas recirculation performance and optimum exhaust gas recirculation rate determination method [PDF]

open access: yesRoyal Society Open Science, 2019
In order to study the exhaust gas recirculation (EGR) performance of marine diesel engines, a venturi high-pressure EGR device was established to overcome the exhaust gas reflow problem based on a certain type of turbocharged diesel engine.
Xiang-huan Zu   +3 more
doaj   +1 more source

A comparison of extremal optimization with flat-histogram dynamics for finding spin-glass ground states

open access: yes, 2002
We compare the performance of extremal optimization (EO), flat-histogram and equal-hit algorithms for finding spin-glass ground states. The first-passage-times to a ground state are computed. At optimal parameter of tau=1.15, EO outperforms other methods
Bak P.   +27 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Constrained Engineering Optimization Algorithm Based on Elite Selection

open access: yesJournal of Algorithms & Computational Technology, 2014
Many engineering optimization problems can be state as function optimization with constrained, intelligence optimization algorithm can solve these problems well.
Xuesong Yan   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy