Results 71 to 80 of about 2,303,688 (304)
Distributed multilevel optimization for complex structures [PDF]
, 2007 Optimization problems concerning complex structures with many design variables may entail an unacceptable computational cost. This problem can be reduced considerably with a multilevel approach: A structure consisting of several components is optimized ...
Akçay Perdahcıoğlu, D. +2 more
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Robotics: Science and Systems I, 2005 Synthesis of robots may be decomposed into two processes: {\em structural synthesis} (determine the general arrangement of the mechanical structure such as the type and number of joints and the way they will be connected) and {\em dimensional synthesis} (determine the length of the links, the axis and location of the joints, the necessary maximal joint
openaire +2 more sources
Multibody System Dynamics, 2002 The paper presents a methodology which is based on a constrained optimization algorithm where the constraints are the maximum valve lift and timing. The objective is to maximize the time integral of valve area opened to gas flow. Once the optimal lift is known, the cam profile can be developed using inverse kinematic analysis. Finally, the authors give
Cardona, Alberto +2 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Blinatumomab is a bispecific T‐cell engager approved for the treatment of pediatric B‐cell acute lymphoblastic leukemia (B‐ALL). Outpatient home infusion reduces hospitalization burden and optimizes resource utilization, but is logistically challenging.
Angela Parra del Riego +10 more
wiley +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley +1 more source
Molecules, 2017 Pyrazino[2,1-a]isoquinolin analogues were reported as potent activators of Nrf2/ARE signaling both in vitro and in vivo by our group. In this study, we simplified the ring system to investigate the functions of various parts of the pyrazino[2,1-a ...
Hongbin Dai +4 more
doaj +1 more source
Optimization of patch antennas via multithreaded simulated annealing based design exploration [PDF]
, 2017 In this paper, we present a new software framework for the optimization of the design of microstrip patch antennas. The proposed simulation and optimization framework implements a simulated annealing algorithm to perform design space exploration in order
Richie, James, Ababei, Cristinel
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Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Identification of Inhibitors of the Anti-Infective Target DXS Using Dynamic Combinatorial Chemistry
Proceedings, 2019 Antibiotic resistance is one of the biggest threats to humankind [1,2]. [...]
Ravindra P. Jumde +3 more
doaj +1 more source
Reliability Based Design Optimization of Concrete Mix Proportions Using Generalized Ridge Regression Model [PDF]
, 2015 This paper presents Reliability Based Design Optimization (RBDO) model to deal with uncertainties involved in concrete mix design process. The optimization problem is formulated in such a way that probabilistic concrete mix input parameters showing ...
Aggarwal, R. (Rachna) +3 more
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