Results 41 to 50 of about 799,975 (268)

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye   +33 more
wiley   +1 more source

Optimization methods and algorithms

open access: yesCentral European Journal of Operations Research
AbstractRecent results of three areas, pickup and delivery, optimal mass transportation, matching under preferences are highlighted. The topics themselves have been selected from the active research fields of Hungarian Operations Research. We also provide a short summary of selected research results from the 34th Hungarian Operations Research ...
Péter Biró 0001   +3 more
openaire   +3 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

An optimal method for stochastic composite optimization [PDF]

open access: yesMathematical Programming, 2011
The stochastic composite optimization problem under consideration consists in minimizing the sum \(f+h\) of two convex functions \(f,h\) defined on a compact convex set \(X\subset \mathbb{R}^{n}\), assuming that \(\nabla f\) and \(h\) are globally Lipschitz.
openaire   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Multi-Objective Optimization of Urban Air Transportation Networks Under Social Considerations

open access: yesIEEE Open Journal of Intelligent Transportation Systems
This work proposes and investigates a solution approach to the urban air transportation network optimization problem, considering the perspectives of different stakeholders, including societal interests.
Nikolas Hohmann   +3 more
doaj   +1 more source

System approach to building a mathematical model of a complex organizational-technical system in transport [PDF]

open access: yesITM Web of Conferences
The current situation in the synthesis of complex organizational and technical systems in transport is characterized by a significant lag in the level of development of special mathematical and software, which significantly reduces the pace of ...
Zhukov Aleksandr   +4 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Machine Learning in Quasi-Newton Methods

open access: yesAxioms
In this article, we consider the correction of metric matrices in quasi-Newton methods (QNM) from the perspective of machine learning theory. Based on training information for estimating the matrix of the second derivatives of a function, we formulate a ...
Vladimir Krutikov   +4 more
doaj   +1 more source

A model for describing the administration and processing system of information generated when responding to incidents by fire departments [PDF]

open access: yesITM Web of Conferences
Firefighting units are a specific object of management that performs its functions in response in conditions of limited time and intensive flow of information.
Gelek Sergey   +2 more
doaj   +1 more source

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