Results 51 to 60 of about 799,975 (268)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

GPX-ADMM-Net: Interpretable Deep Neural Network for Image Compressive Sensing

open access: yesIEEE Access, 2021
The building of effective neural network architectures for solving image compressive sensing (CS) problems is a challenge. Hence, it is helpful to consult the structural insight provided by traditional optimization algorithms, the results of which are ...
Shih-Wei Hu   +2 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Numerical Methods for Optimization of the Horizontal Directional Drilling (HDD) Well Path Trajectory

open access: yesEnergies, 2020
Advances in the field of material engineering, computerization, automation, and equipment miniaturization enable modernization of the existing technologies and development of new solutions for construction, inspection, and renovation of underground ...
Rafał Wiśniowski   +2 more
doaj   +1 more source

Comparative analysis of optimization methods for electrical energy losses interval evaluation problem [PDF]

open access: yesКомпьютерные исследования и моделирование, 2013
This article is dedicated to a comparison analysis of optimization methods, in order to perform an interval estimation of electrical energy technical losses in distribution networks of voltage 6-20 kV. The issue of interval evaluation is represented as a
Yuri Vladimirovich Koltsov   +1 more
doaj   +1 more source

Performance of Domain-Wall Encoding for Quantum Annealing

open access: yesIEEE Transactions on Quantum Engineering, 2021
In this article, we experimentally test the performance of the recently proposed domain-wall encoding of discrete variables Chancellor, 2019, on Ising model flux qubit quantum annealers.
Jie Chen   +2 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Pre-Selection of the Optimal Sitting of Phase-Shifting Transformers Based on an Optimization Problem Solved within a Coordinated Cross-Border Congestion Management Process

open access: yesEnergies, 2020
The current European policy roadmap aims at forcing the TSOs to coordinate remedial actions used for relieving the congestions in the synchronous power system.
Endika Urresti-Padrón   +3 more
doaj   +1 more source

SCATTERING BY CIRCULAR VOIDS WITH RIGID BOUNDARY: DIRECT AND INVERSE PROBLEMS FOR OPEN AND CLOSE DOMAINS

open access: yesInformatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska, 2022
Problems with the accuracy of calculations by the Boundary Element Method of acoustic and ultrasonic problems formulated in the frequency domain were presented in this paper.
Tomasz Rymarczyk, Jan Sikora
doaj   +1 more source

On the optimization of an extrapolation method

open access: yesLinear Algebra and its Applications, 1984
AbstractWe consider an extrapolation method, based on a linear stationary iterative method of first degree, for the numerical solution of the linear system Au=b. We obtain upper bounds for the minimum spectral radius of the extrapolation method as well as good optimum values for the extrapolation parameter.
openaire   +2 more sources

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