Results 71 to 80 of about 61,587 (303)
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
The Euro Zone Eastern Enlargement: Challanges to Current Members and the ECB [PDF]
Romanian Journal of European Affairs, 2006 The eastward enlargement of the euro area entails significant implications both for acceding countries and for the current euro area member States or for the European Central Bank.
Mihai Sebea
doaj
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
OPTIMUM CURRENCY AREA INDICES : EVIDENCE FROM THE 1990s [PDF]
In this paper the authors calculate OCA-indexes for industrial countries in an effort to estimate the benefit-cost ratio of adopting a common currency. The results correspond to the estimation of Bayoumi and Eichengreen (1997b) and show that the ranking ...
Horváth, Roman, Komárek, Luboš
core
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Public Debt Evolution in the Eurozone and the Need of Policy Coordination [PDF]
Theoretical and Applied Economics, 2010 The Eurozone sustainability could become a real challenge in the current economical environment, characterized by uncertainty and lack of credibility. The issue of public debts represents a threat for the European financial system, while the coordination
Andrei HREBENCIUC
doaj +1 more source
The euro: It can't happen, It's a bad idea, It won't last. US economists on the EMU, 1989-2002 [PDF]
This study of approximately 170 publications shows (a) that US academic economists concentrated on the question "Is the EMU a good or bad thing?", usually adopting the paradigm of optimum currency areas as their main analytical vehicle, (b) that they ...
Eoin Drea, Lars Jonung
core
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
An Empirical Analysis of Romania’s Comovement with the Euro Zone [PDF]
Theoretical and Applied Economics, 2009 In light of adopting the euro in the near future, it is important to asses to which extent the Romanian business cycle evolves in a similar fashion with that of the euro zone.
Nicolae Dardac, Elena Bojesteanu
doaj +1 more source