Results 91 to 100 of about 16,578,662 (358)
An optimization method for dynamics of structures with repetitive component patterns [PDF]
, 2009 The occurrence of dynamic problems during the operation of machinery may have devastating effects on a product. Therefore, design optimization of these products becomes essential in order to meet safety criteria.
Akcay Perdahcioglu, D. +3 more
core +4 more sources
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
ActuatorsIn addressing the design challenges for constant-stress accelerated life testing in non-rectangular experimental domains, we aim to optimize the precision in estimating parameters for the product reliability statistical model. Following the principles of
Ping Qian +4 more
doaj +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Effects of local reinforcement on nozzles in dished ends [PDF]
, 2009 The results of a parametric design study, to determine the optimum diameter of reinforcing pad for nozzles in the knuckle region of an ellipsoidal pressure vessel head are presented herein.
Hitchen, J, Nash, D H
core
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Shape Synthesis in Mechanical Design
Acta Polytechnica, 2007 The shaping of structural elements in the area of mechanical design is a recurrent problem. The mechanical designer, as a rule, chooses what is believed to be the “simplest” shapes, such as the geometric primitives: lines, circles and, occasionally ...
C. P. Teng, S. Bai, J. Angeles
doaj
Optimum design and performance of a base-isolated structure with tuned mass negative stiffness inerter damper. [PDF]
Sci Rep, 2023 Kiran KK, Al-Osta MA, Ahmad S.
europepmc +1 more source
Optimum design criteria for solar hot water systems [PDF]
, 1996 This paper is concerned with the optimisation of some design criteria of SHW systems intended for residential and hotel applications. For this purpose, a system model based on TRNSYS programme has been used to correlate the performance and cost ...
Michaelides, Ioannis, Wilson, Derek R.
core +2 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source