Results 21 to 30 of about 31,983 (250)

An Optimum Projection and Noise Reduction Approach for Detecting Rare and Common Variants Associated with Complex Diseases [PDF]

Human Heredity, 2012
<b><i>Background:</i></b> Despite the thrilling advances in identifying gene variants that influence common diseases, most of the heritable risk for many common diseases still remains unidentified. One of the possible reasons for this missing heritability is that the genome-wide association study (GWAS) approaches have been ...
Asuman, Turkmen, Shili, Lin
openaire   +2 more sources

Hybrid Algorithm of Particle Swarm Optimization and Grey Wolf Optimizer for Improving Convergence Performance

Journal of Applied Mathematics, 2017
A newly hybrid nature inspired algorithm called HPSOGWO is presented with the combination of Particle Swarm Optimization (PSO) and Grey Wolf Optimizer (GWO).
Narinder Singh, S. B. Singh
doaj   +1 more source

Enantioselective Biosynthesis of L-Phenyllactic Acid From Phenylpyruvic Acid In Vitro by L-Lactate Dehydrogenase Coupling With Glucose Dehydrogenase

Frontiers in Bioengineering and Biotechnology, 2022
As a valuable versatile building block, L-phenyllactic acid (L-PLA) has numerous applications in the fields of agriculture, pharmaceuticals, and biodegradable plastics. However, both normally chemically synthesized and naturally occurring PLA are racemic,
Dong Zhang, Ting Zhang, Yuqing Lei, Wenqian Lin, Xingyi Chen, Minchen Wu   +5 more
doaj   +1 more source

Multiclass characterization of frontotemporal dementia variants via multimodal brain network computational inference

Network Neuroscience, 2023
Characterizing a particular neurodegenerative condition against others possible diseases remains a challenge along clinical, biomarker, and neuroscientific levels.
Raul Gonzalez-Gomez, Agustín Ibañez, Sebastian Moguilner   +2 more
doaj   +1 more source

Signet ring cell cancer of Ampulla of Vater—first ever case reported in a teenager and a review of literature

Rare Tumors, 2021
Ampullary cancers are rare accounting for 0.2% of all gastrointestinal cancers. Signet ring is a rare variant of adenocarcinoma, characterized by having more than 50% of mucin secreting cells and clinically having a worse prognosis.
Asad Ali Kerawala, Abid Jamal, Lubna Saleem   +2 more
doaj   +1 more source

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach   +15 more
wiley   +1 more source

Axial-Flow Pump with Enhanced Cavitation Erosion Resistance

Energies, 2023
Axial-flow pumps, in addition to providing high anti-cavitation properties, must have high anti-erosion properties to ensure the required lifetime of the pump.
Aleksandr Zharkovskii, Dmitry Svoboda, Igor Borshchev, Arsentiy Klyuyev, Evgeniy Ivanov, Sergey Shutsky   +5 more
doaj   +1 more source

Early Body Mass Index z‐Score Change and Resolution of Severe Malnutrition in Children With Sickle Cell Anemia in a Low‐Income Setting: A Prospective Single‐Arm Extension Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell anemia (SCA) in low‐income settings are at risk of severe malnutrition, but optimal nutritional management has not been established. We evaluated an intensified ready‐to‐use therapeutic food (RUTF) regimen in children with persistent severe malnutrition after initial treatment and assessed whether early ...
Safiya Gambo, Shehu Umar Abdullahi, Hassan Adam Murtala, Halima Kabir, Khadija A. Shamsu, Sari A. Acra, Virginia A. Stallings, Mark Rodeghier, Michael R. DeBaun, Lauren J. Klein   +9 more
wiley   +1 more source

Immobilization of Naringinase from Penicillium decumbens on Chitosan Microspheres for Debittering Grapefruit Juice

Molecules, 2019
Naringinase is an enzyme complex which exhibits α-l-rhamnosidase and β-d-glucosidase activity. This enzymatic complex catalyzes the hydrolysis of naringin (4′,5,7-trihydroxy flavanone 7-rhamnoglucoside), the main bittering component in ...
Joanna Bodakowska-Boczniewicz, Zbigniew Garncarek   +1 more
doaj   +1 more source

DES-Based Biocatalysis as a Green Alternative for the l-menthyl Ester Production Based on l-menthol Acylation

Molecules, 2022
The deep eutectic solvent (DES)-based biocatalysis of l-menthol acylation was designed for the production of fatty acid l-menthyl ester (FME) using fatty acid methyl ester (FAME).
Sabina Ion, Florentina Olănescu, Florina Teodorescu, Robert Tincu, Daniela Gheorghe, Vasile I. Pârvulescu, Mădălina Tudorache   +6 more
doaj   +1 more source