Results 181 to 190 of about 235,374 (351)

Sex as a biological variable in nonclinical studies: Bridging scientific rigor, animal welfare, and regulatory expectations

Animal Models and Experimental Medicine, EarlyView.
Sex as a biological variable (SABV) is a critical determinant of pharmacokinetics, pharmacodynamics, and toxicity in nonclinical studies. This review highlights how inappropriate neglect of sex differences compromises animal welfare, scientific reproducibility, and regulatory compliance.
Kenta Onuma, Masaki Watanabe, Nobuya Sasaki   +2 more
wiley   +1 more source

Single port endoscopic transaxillary first rib resection for thoracic outlet syndrome. [PDF]

J Vasc Surg Cases Innov Tech
Carter S, Creisher B, Setia O, Blasberg J, Schwartz J, Strosberg D.   +5 more
europepmc   +1 more source

Probabilistic Lesion Mapping to Optimize Thalamotomy Targets for Focal Hand Dystonia

Annals of Neurology, EarlyView.
Objective Focal hand dystonia (FHD) severely impairs task‐specific motor control, yet the optimal surgical target for stereotactic intervention remains uncertain. This study aimed to identify the precise thalamic lesion site associated with symptomatic improvement and to clarify its network connectivity. Methods We retrospectively analyzed 164 patients
Masahiko Nishitani, Shiro Horisawa, Konstantin Butenko, Hiroki Togo, Arun Garimella, William Drew, Melissa Chua, Esraa Shaban, Takakazu Kawamata, Takaomi Taira, Andreas Horn, Michael D. Fox, Takashi Hanakawa   +12 more
wiley   +1 more source

A Look inside a Flexible Open-Source Scanning Electrochemical Probe Microscope. [PDF]

ACS Electrochem
McKelvey K, Edwards MA, Kang M, Brunet Cabré M, Jones NB, Unwin PR.   +5 more
europepmc   +1 more source

Don’t Mind the Gap: The Rise of Individual Complaint Mechanisms Within International Human Rights Treaties [PDF]

, 2012
Harrington, Alexandra R.
core   +1 more source

Astrocytic Mitochondria Transplantation Rescues Neuron Loss and Dendritic Injuries in Acute Cerebral Ischemic Stroke Mouse Model by Flexibly Regulating Mitochondria Dynamics

Annals of Neurology, EarlyView.
Objective Cerebral ischemic stroke causes neuronal oxygen/energy deprivation, disrupting mitochondrial function including reduced membrane potential and bioenergetics, exacerbating neuronal injury. Mitochondrial defects are, therefore, a central neuropathological node and potential therapeutic target.
Ning Bian, Jianing Shen, Linwei Tian, Jinghui Li, Lu Yang, Bo Yuan, Shulin Li, Yuyu Niu, Lu Zhao, Jingkuan Wei   +9 more
wiley   +1 more source

CROSS BORDER CONTRACTING IN THE EU - INTEROPERABILITY PROBLEMS AND THE IMPACT OF A COMMUNITY WIDE OPTIONAL INSTRUMENT

, 2004
Martin Doris
openalex   +2 more sources

Informal care in different European care systems: Effects of caregiving on mental health over time. [PDF]

PLoS One
Börner L, Kolodziej IWK, Wasem J, Abels C.   +3 more
europepmc   +1 more source

Orchestrating High–Quality Middle School Band Music [PDF]

, 2009
Noyes, Rebecca
core   +2 more sources

Use of Brain MRI in Cerebral Adrenoleukodystrophy: International Recommendations for Screening, Monitoring, and Research. [PDF]

Neurology
Yska HAF, Golse M, Galanaud D, Amartino HM, Bergner C, Bruschi F, Eichler FS, Fatemi A, García-Cazorla À, Gomez-Chiari M, Köhler W, Loes D, Lund T, Mallack EJ, Moscatelli M, Musolino PL, Nascene DR, Orthmann-Murphy JL, Parazzini C, Pouwels PJW, Ribeiro-Constante J, Roosendaal SD, Salsano E, Sgobbi PV, Sevin C, Smith Fine A, Tonduti D, Van Haren K, Zerem A, Engelen M, Mochel F.   +30 more
europepmc   +1 more source