Results 61 to 70 of about 1,773 (193)
Laser-Inscribed Glass Microfluidic Device for Non-Mixing Flow of Miscible Solvents
Micromachines, 2018 In recent years, there has been significant research on integrated microfluidic devices. Microfluidics offer an advantageous platform for the parallel laminar flow of adjacent solvents of potential use in modern chemistry and biology.
Valeria Italia +9 more
doaj +1 more source
Applied Sciences, 2021 Optics and photonics are among the key technologies of the 21st century and offer the potential for novel applications in areas as diverse as sensing and spectroscopy, analytics, monitoring, biomedical imaging and diagnostics, as well as optical ...
Lourdes S. M. Alwis +2 more
doaj +1 more source
Biotechnology and Bioengineering, EarlyView.ABSTRACT The glutamine synthetase expression system is widely used for therapeutic protein biomanufacturing in Chinese hamster ovary (CHO) cells. Here, we present the design of an enhanced glutamine synthetase vector for generating CHOK1SV GS‐KO stable pools that produce recombinant proteins at multigram‐per‐liter levels. We first developed a synthetic
Yusuf B. Johari +11 more
wiley +1 more source
Optical Properties of Buffers and Cell Culture Media for Optofluidic and Sensing Applications
Applied Sciences, 2019 Interactions between light and various cells in cultures, such as bacteria or mammalian cells, are widely applied for optical sensors and optofluidic systems.
Van Thuy Hoang +8 more
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Biotechnology Progress, EarlyView.Abstract Development of therapeutic bispecific antibodies (BsAbs) poses significant manufacturability challenges associated with correct chain pairing and an increased diversity of impurities. Here we address this with a product quality assessment during cell line development (CLD), forgoing the need for genetic characterization during cell line ...
Molly Robinson +7 more
wiley +1 more source
Optofluidic on-chip tomography [PDF]
2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2011 The first demonstration of optofluidic tomography is presented. Using partially coherent illumination, holograms of objects are recorded at multiple viewing angles, as they flow through a microfluidic channel placed directly on the top of an opto-electronic sensor array.
Isikman, S. O. +3 more
openaire +2 more sources
Photothermal bubble: Dynamics, manipulation, and applications
Droplet, EarlyView.As a versatile platform for bubble manipulation, photothermal techniques empower diverse operations: planar translation by scanning the laser spot, sustained periodic bouncing from competing thermal and hydrodynamic flows, and even guided 3D trajectories achieved by tailoring the heating configuration.
Man Hu, Feng Wang, Daosheng Deng
wiley +1 more source
Optofluidic Single-Cell Genome Amplification of Sub-micron Bacteria in the Ocean Subsurface
Frontiers in Microbiology, 2018 Optofluidic single-cell genome amplification was used to obtain genome sequences from sub-micron cells collected from the euphotic and mesopelagic zones of the northwestern Sargasso Sea.
Zachary C. Landry +9 more
doaj +1 more source
Raman-based sorting of microbial cells to link functions to their genes
Microbial Cell, 2020 In our recent work, we developed an optofluidic platform that allows a direct link to be made between the phenotypes (functions) and the genotypes (genes) of microbial cells within natural communities.
Kang Soo Lee +2 more
doaj +1 more source
Optofluidic Tomography on a Chip [PDF]
Applied Physics Letters, 2011 Using lensfree holography we demonstrate optofluidic tomography on a chip. A partially coherent light source is utilized to illuminate the objects flowing within a microfluidic channel placed directly on a digital sensor array. The light source is rotated to record lensfree holograms of the objects at different viewing directions. By capturing multiple
Serhan O, Isikman +3 more
openaire +2 more sources