Results 141 to 150 of about 704,312 (278)

Theta oscillations, epileptogenesis, and focal seizures in rodent models of mesial temporal lobe epilepsy

Epilepsia, EarlyView.
Abstract Theta oscillations (4–12 Hz) are a prominent network rhythm within hippocampal and parahippocampal structures. Driven by cholinergic and γ‐aminobutyric acidergic inputs originating from the medial septum, physiological theta gates network excitability to control spatial navigation, memory encoding, and sensorimotor integration during specific ...
Maxime Lévesque, Massimo Avoli
wiley   +1 more source

Combined Optogenetic and Electrical Stimulation of the Auditory Nerve for Cochlear Implants

© 2024 Elise Asiat AjayCochlear implants restore hearing to people with hearing impairments all over the world. Although this technology has drastically improved their quality of life, users still struggle to understand speech in noisy environments and ...
Ajay, Elise Asiat
core   +1 more source

Timing is everything: The effect of early‐life seizures on developing neuronal circuits subserving spatial memory

Epilepsia Open, EarlyView.
Abstract Spatial memory, the aspect of memory involving encoding and retrieval of information regarding one's environment and spatial orientation, is a complex biological function incorporating multiple neuronal networks. Hippocampus‐dependent spatial memory is not innate and emerges during development in both humans and rodents.
Gregory L. Holmes
wiley   +1 more source

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

Artificial intelligence in preclinical epilepsy research: Current state, potential, and challenges

Epilepsia Open, EarlyView.
Abstract Preclinical translational epilepsy research uses animal models to better understand the mechanisms underlying epilepsy and its comorbidities, as well as to analyze and develop potential treatments that may mitigate this neurological disorder and its associated conditions. Artificial intelligence (AI) has emerged as a transformative tool across
Jesús Servando Medel‐Matus, Cesar Santana‐Gomez, Ruby G. Escalante, Dominique Duncan, Pedro F. Viana, Giulia Sofia Cereda, Naoto Kuroda, Aristea S. Galanopoulou   +7 more
wiley   +1 more source

The basal ganglia and the epilepsies

Epilepsia Open, EarlyView.
Abstract The basal ganglia are an evolutionarily conserved neural circuit best known for the selection and sequencing of voluntary movement. Increasing evidence, however, indicates that these structures also play an important role in regulating pathological brain states, including seizures.
Willian Lazarini‐Lopes, Logan Perry, Patrick A. Forcelli   +2 more
wiley   +1 more source

Advancing super‐resolution stimulated emission depletion microscopy with luminescent lanthanide nanocrystals

FlexMat, EarlyView.
The state‐of‐the‐art research advances and its cutting‐edge application in super resolution stimulated emission depletion technology based on luminescent lanthanide nanocrystals. Abstract Stimulated emission depletion (STED) microscopy overcomes the diffraction limit to reveal subcellular structures beyond the reach of conventional optical methods ...
Yaqi Chen, Tengfei Ma, Shuping Huang, Wei Guo, Yiming Wu   +4 more
wiley   +1 more source

Body‐integrated photonic biosensors: Illuminating the path to active healthcare

FlexMat, EarlyView.
Body‐integrated photonic biosensors are promising tools for active healthcare. These optical devices can be worn, implanted, or swallowed to monitor health signals continuously. This review introduces key sensing modalities, including fluorescence, colorimetry, SPR, LSPR, SERS, and light‐modulating materials.
Jiayue Gu, Xingming Wen, Qihang Yan, Yining Zhao, Linghao Yuan, Siyuan Chen, Yue Ma, Zhengyue Fang, Dong Lei, Yuxin Liu, Ze Xiong   +10 more
wiley   +1 more source

Recent advances in flexible optoelectronic synapses: Mechanisms, materials, and neuromorphic applications

FlexMat, EarlyView.
Flexible optoelectronic synapses integrate sensing, memory, and computation within mechanically compliant devices. This review summarizes their neuromorphic mechanisms and recent advances in diverse material platforms, emphasizing stability challenges under coupled optical, electrical, mechanical, and environmental stresses.
Yingjie Li, Yuyi Feng, Daquan Yang, Wenqiang Yang, Rui Su, Meicheng Li, Caofeng Pan   +6 more
wiley   +1 more source

Organic electrochemical transistors for neural recording and modulation: From mixed‐conduction physics to closed‐loop biointerfaces

InfoMat, EarlyView.
OECT‐based neural interfaces integrate mixed ionic‐electronic transduction, soft biointegration, multimodal sensing, and closed‐loop modulation, enabling adaptive recording, neurochemical monitoring, and intelligent therapeutic strategies. Abstract Next‐generation neural interfaces increasingly aim to couple neural recording with local processing and ...
Chao Zhao, Zhongqing Sun, Shijie Wang, Bingjun Wang, Zixuan Yuan, Yaomin Guo, Jie Zhao, Leyuan Li, Xiaomu Wang, Wen Jiang, Wei Ma   +10 more
wiley   +1 more source