Results 161 to 170 of about 704,312 (278)

Optogenetic stimulation of Lbc GEF-mediated Rho activity dynamics promotes cell invasion. [PDF]

open access: yesMol Biol Cell
Wagner J   +6 more
europepmc   +1 more source

Post‐Trial Responsibilities for Participants Implanted With Neurosurgical Devices: A Qualitative Study

open access: yesBioethics, EarlyView.
ABSTRACT The issue of post‐trial responsibility is about what is owed to research participants after a clinical trial ends, who is responsible, and how long this responsibility must endure. Despite two decades of international guidance on this issue, research involving novel high‐risk interventions—such as implantable neurotechnologies—raises ...
Nathan Higgins   +2 more
wiley   +1 more source

Cannabigerol reverses mechanical allodynia through α2A‐adrenergic modulation of thalamocortical signaling in chemotherapy‐induced neuropathy

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and treatment‐resistant side effect of platinum‐based chemotherapy, characterised by mechanical allodynia. Cannabigerol (CBG), a non‐psychoactive cannabinoid, has shown antinociceptive potential, but its site and mechanism of action remain unclear.
Quinn W. Wade   +7 more
wiley   +1 more source

Effects of optogenetic stimulation on neural gene expression in human bone marrow and adipose-derived mesenchymal stem cells. [PDF]

open access: yesBMC Biotechnol
Fereidounian MA   +6 more
europepmc   +1 more source

Peripheral targets for neuropathic pain

open access: yesBritish Journal of Pharmacology, EarlyView.
Neuropathic pain represents a significant clinical challenge, with still limited pharmacological approaches to symptomatic relief. This review focuses on molecular targets implicated in neuropathic pain, particularly those involved in peripheral mechanisms. Using the IUPHAR/BPS database of biological targets, their occurrence together with ‘neuropathic
Amirhossein Afsharipour   +3 more
wiley   +1 more source

Strategies for optogenetic stimulation of deep tissue peripheral nerves

open access: yes, 2018
Thesis: Ph. D., Harvard-MIT Program in Health Sciences and Technology, 2018.Cataloged from PDF version of thesis.Includes bibliographical references (pages 181-190).Optogenetic technologies have been the subject of great excitement within the scientific ...
Maimon, Benjamin E
core  

Therapeutic access points: The roles of circumventricular organs in drug delivery and metabolic regulation

open access: yesBritish Journal of Pharmacology, EarlyView.
The current obesity drug landscape, dominated by GLP‐1 receptor agonists and emerging multi‐agonist therapies, has reinforced that long‐term weight loss is achieved in large part through central mechanisms that suppress appetite and reshape energy balance.
Ines Martinez‐Corral   +3 more
wiley   +1 more source

Algal Eyes

open access: yesMajor Reference Works., 2011

Wiley is pleased to announce the recent acquisition of the prestigious Encyclopedia of Life Sciences (ELS) from the Nature Publishing Group.

"The most ambitious single source reference source ever produced in the biological sciences"
—American Reference Books Annual

Spanning the entire spectrum of life science ...
Peter Hegemann, Carol Dieckmann
wiley  

+1 more source

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