Panic disorder (PD) is an acute paroxysmal anxiety disorder with poorly understood pathophysiology. The dorsal periaqueductal gray (dPAG) is involved in the genesis of PD.
Zhou, Rui +23 more
core
Looking for trouble: A common threat‐detection mechanism underlying pain, fear, and anxiety
I put forward a novel cognitive architecture for pain, fear, and anxiety, according to which these three capacities are underpinned by a common threat‐detection mechanism. This mechanism takes information about potential threats as input, assesses whether the threat is actual and, if it deems it is, outputs a threat representation.
Luca Barlassina
wiley +1 more source
Optogenetic stimulation of midbrain dopaminergic neurons rescues hippocampal synaptic plasticity deficits in a mouse model of Alzheimer's disease. [PDF]
Ficchì S +11 more
europepmc +1 more source
Considering optogenetic stimulation for cochlear implants
Electrical cochlear implants are by far the most successful neuroprostheses and have been implanted in over 300,000 people worldwide. Cochlear implants enable open speech comprehension in most patients but are limited in providing music appreciation and speech understanding in noisy environments.
Jeschke, Marcus, Moser, Tobias
openaire +1 more source
Guard cell size and initial conductance influence stomatal closure kinetics
Conceptual overview of the two hypotheses linking stomatal anatomy to closure kinetics. Summary In fluctuating environments, the kinetics of stomatal opening and closing influence the balance between carbon gain and water loss. Smaller guard cells may respond faster to fluctuating environmental conditions because of their greater surface area for ...
Christopher D. Muir, Wei Shen Lim
wiley +1 more source
Automatic OptoDrive for Extracellular Recordings and Optogenetic Stimulation in Freely Moving Mice. [PDF]
Caballero-Ruiz A +7 more
europepmc +1 more source
Calcium‐activated chloride channels in pericytes and their role in regulating organ blood flow
Abstract figure legend Pericytes are microvascular mural cells with diverse roles. Contractile pericytes directly regulate local perfusion, while non‐contractile pericytes coordinate upstream vascular contractility via propagating electrical signals.
Paolo Tammaro, Hikaru Hashitani
wiley +1 more source
A wireless optogenetic stimulation system for long-term function evaluation of mice forelimb with sub-nerve resolution. [PDF]
Zhou M +12 more
europepmc +1 more source
Development and validation of stimulation strategies for the optogenetics
Conception et validation de stratégies de stimulation pour l'optogénétique Un million et demi de personnes souffrent de la Rétinopathie Pigmentaire, une famille de maladies héréditaires entraînant une dégénérescence de la rétine. La maladie commence par la perte de la vision nocturne et du champ visuel périphérique et mène à une cécité ...
openaire +2 more sources
Update on cellular expression and function of ANO1 channels in urethral smooth muscle
Abstract figure legend Activation of ANO1 channels and resulting Cl− efflux are suggested to modulate urethral smooth muscle contractility by enhancing Ca2+ influx via voltage‐dependent Ca2+ entry and resulting contraction in urethral smooth muscle cells.
Bernard T. Drumm, Neha Gupta
wiley +1 more source

