Results 101 to 110 of about 55,224 (387)

Interrogating cellular perception and decision making with optogenetic tools. [PDF]

open access: yes, 2017
Optogenetics promises to deepen our understanding of how cells perceive and respond to complex and dynamic signals and how this perception regulates normal and abnormal function.
Bugaj, Lukasz J   +2 more
core  

Fighting against fast speckle decorrelation for light focusing inside live tissue by photon frequency shifting [PDF]

open access: yes, 2020
Light focusing inside live tissue by digital optical phase conjugation (DOPC) has drawn increasing interest due to its potential biomedical applications in optogenetics, microsurgery, phototherapy, and deep-tissue imaging.
Cheng, Zhongtao   +5 more
core   +1 more source

Advances in Photonic Materials and Integrated Devices for Smart and Digital Healthcare: Bridging the Gap Between Materials and Systems

open access: yesAdvanced Materials, EarlyView.
This article summarizes significant technological advancements in materials, photonic devices, and bio‐interfaced systems, which demonstrate successful applications for impacting human healthcare via improved therapies, advanced diagnostics, and on‐skin health monitoring.
Seunghyeb Ban   +5 more
wiley   +1 more source

New insights into cochlear sound encoding [version 1; referees: 2 approved]

open access: yesF1000Research, 2016
The inner ear uses specialized synapses to indefatigably transmit sound information from hair cells to spiral ganglion neurons at high rates with submillisecond precision.
Tobias Moser, Christian Vogl
doaj   +1 more source

Optogenetics — The Might of Light

open access: yesNew England Journal of Medicine, 2021
Optogenetics Recognized through the Lasker Award This year’s Lasker Basic Medical Research Award goes to Drs.
openaire   +4 more sources

Materials Advances in Devices for Heart Disease Interventions

open access: yesAdvanced Materials, EarlyView.
This review examines the crucial role of materials in heart disease interventions, focusing on strategies for monitoring, managing, and repairing heart conditions. It discusses the material requirements for medical devices, highlighting recent innovations and their impact on cardiovascular health.
Gagan K. Jalandhra   +11 more
wiley   +1 more source

Nano‐optogenetic immunotherapy

open access: yesClinical and Translational Medicine, 2022
Chimeric antigen receptor (CAR) T cell‐based immunotherapy has been increasingly used in the clinic for cancer intervention over the past 5 years. CAR T‐cell therapy takes advantage of genetically‐modified T cells to express synthetic CAR molecules on the cell surface.
Kai Huang   +3 more
openaire   +4 more sources

Subcellular optogenetic activation of Cdc42 controls local and distal signaling to drive immune cell migration [PDF]

open access: yes, 2016
Migratory immune cells use intracellular signaling networks to generate and orient spatially polarized responses to extracellular cues. The monomeric G protein Cdc42 is believed to play an important role in controlling the polarized responses, but it has
Gautam, N.   +2 more
core   +2 more sources

Unlocking Multimodal Nonlinear Microscopy for Deep‐Tissue Imaging under Continuous‐Wave Excitation with Tunable Upconverting Nanoparticles

open access: yesAdvanced Materials, EarlyView.
This study introduces a multimodal nonlinear microscopy approach using upconverting nanoparticles (UCNPs) under continuous‐wave excitation. The UCNPs exhibit high‐order nonlinear optical responses, enabling deep‐tissue 3D imaging, video‐rate wide‐field imaging, and depth‐selective photomodulation.
Jeongmo Kim   +13 more
wiley   +1 more source

A companion to the preclinical common data elements for rodent models of pediatric acquired epilepsy: A report of the TASK3‐WG1B, Pediatric and Genetic Models Working Group of the ILAE/AES Joint Translational Task Force

open access: yesEpilepsia Open, EarlyView., 2022
Abstract Epilepsy syndromes during the early years of life may be attributed to an acquired insult, such as hypoxic–ischemic injury, infection, status epilepticus, or brain trauma. These conditions are frequently modeled in experimental rodents to delineate mechanisms of epileptogenesis and investigate novel therapeutic strategies.
Anna‐Maria Katsarou   +7 more
wiley   +1 more source

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