Results 81 to 90 of about 28,083 (286)
Optogenetics: Therapeutic spark in neuropathic pain
Biomolecules & Biomedicine, 2019 Optogenetics is an emerging field, which uses light and molecular genetics to manipulate the activity of live cells by expressing light-sensitive proteins.
Kang Liu, Long Wang
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Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair
Advanced Science, EarlyView.We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing +10 more
wiley +1 more source
Optogenetics and Its Transformative Role in Tissue Engineering and Regenerative Medicine
Nano SelectOptogenetics, a revolutionary technique leveraging light stimulation for precise cellular control, holds immense potential in regenerative medicine. Offering unparalleled spatial and temporal accuracy, the entrance of optogenetics into tissue engineering
Emine Camcıoglu +2 more
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Advanced Science, EarlyView.Palatable food alleviates stress and prevents anxiety. This study uncovers a dedicated neural pathway: dopamine release in the PFC activates D1R neurons, whose projections to the peri‐PVN engage a population of anxiolytic CRFR1 neurons. These neurons then inhibit stress‐induced hyperactivity of PVNCRF neurons, providing a circuit‐level explanation for ...
Yuchuan Hong +12 more
wiley +1 more source
Exploring adult hippocampal neurogenesis using optogenetics [PDF]
, 2018 In the 1980s, it was widely accepted that new neurons are continuously generated in the dentate gyrus of the mammalian hippocampus. Since its acceptance, researchers have employed various techniques and behavioral paradigms to study the proliferation ...
Pinardo, Heinrich
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Optogenetics and its Applications in Psychology: Manipulating the Brain Using Light
Journal of European Psychology Students, 2013 In a broad sense, optogenetics uses genetically addressable photosensitive tools to monitor and control activity of living cells and tissue. This paper focuses on causal manipulation of neural populations by delivering light to light-sensitive ion ...
Sander Lamballais
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Optogenetics in Neural Systems [PDF]
, 2011 Both observational and perturbational technologies are essential for advancing the understanding of brain function and dysfunction. But while observational techniques have greatly advanced in the last century, techniques for perturbation that are matched
Fenno, Lief E. +9 more
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Advanced Science, EarlyView.Employing a digital single‐molecule activity tracker (dSMAT), this research demonstrates that high‐photon‐flux irradiation drives progressive oxidative scarring in polymerases. Unlike simple thermal denaturation, real‐time kinetic tracking dynamically visualizes enzymes degrading into multiple impaired subpopulations.
Anran Zheng +11 more
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Optogenetics: Novel Tools for Controlling Mammalian Cell Functions with Light
International Journal of Photoenergy, 2014 In optogenetics, targeted illumination is used to control the functions of cells expressing exogenous light-activated proteins. Adoption of the optogenetic methods has expanded rapidly in recent years.
Toshihiro Kushibiki +3 more
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Advanced Science, EarlyView.This study identifies an anterior cingulate cortex (ACC) to anterior insular cortex (AIC) glutamatergic (Glu) circuit that gates stress induced visceral hypersensitivity and anxiety. Circuit activation induces both phenotypes, whereas inhibition relieves them.
Junwen Wang +8 more
wiley +1 more source