Results 81 to 90 of about 44,262 (332)
MRI-guided robotic arm drives optogenetic fMRI with concurrent Ca2+ recording
Nature Communications, 2019 Fiber optic implantation in deep areas of the rodent’s brain for MRI combined with optogenetics is challenging. Here the authors use an MRI-guided robotic arm as the navigation method for accurate fiber optic placement and precise microinjection during ...
Yi Chen +4 more
doaj +1 more source
Striatal cholinergic interneurons generate beta and gamma oscillations in the corticostriatal circuit and produce motor deficits [PDF]
, 2016 Cortico-basal ganglia-thalamic (CBT) neural circuits are critical modulators of cognitive and motor function. When compromised, these circuits contribute to neurological and psychiatric disorders, such as Parkinson's disease (PD).
Bucklin, Mark +5 more
core +1 more source
Ultrasound Modulation of Visual Circuits in Mice Independent of Auditory Confound
Advanced Science, EarlyView.In this study, Qiu et al. found that low‐intensity ultrasound can directly activate sparse ultrasound‐sensitive neurons (UNs) in the primary visual cortex (V1) of deafened mice. The proportion of these sparse UNs is pressure‐dependent. Furthermore, ultrasound modulates visual circuitry with distinct excitatory and inhibitory effects.
Jiaru He +8 more
wiley +1 more source
Optogenetics and Its Transformative Role in Tissue Engineering and Regenerative Medicine
Nano SelectOptogenetics, a revolutionary technique leveraging light stimulation for precise cellular control, holds immense potential in regenerative medicine. Offering unparalleled spatial and temporal accuracy, the entrance of optogenetics into tissue engineering
Emine Camcıoglu +2 more
doaj +1 more source
Optogenetics: Therapeutic spark in neuropathic pain
Biomolecules & Biomedicine, 2019 Optogenetics is an emerging field, which uses light and molecular genetics to manipulate the activity of live cells by expressing light-sensitive proteins.
Kang Liu, Long Wang
doaj +1 more source
A Tac1‐Expressing Brainstem Pathway Underlies the Pathogenesis of Trigeminal Neuralgia
Advanced Science, EarlyView.A critical TG‐Sp5CTac1‐PBNTac1 pathway drives trigeminal neuropathic pain (TNP). Tac1‐expressing parabrachial nucleus (PBNTac1) neurons exhibit heightened responses to innocuous stimuli in TNP, and chemogenetic inhibition of these neurons effectively prevents TNP development.
Liting Sun +11 more
wiley +1 more source
Optogenetics and its Applications in Psychology: Manipulating the Brain Using Light
Journal of European Psychology Students, 2013 In a broad sense, optogenetics uses genetically addressable photosensitive tools to monitor and control activity of living cells and tissue. This paper focuses on causal manipulation of neural populations by delivering light to light-sensitive ion ...
Sander Lamballais
doaj +1 more source
Spatio-temporal, optogenetic control of gene expression in organoids [PDF]
, 2021 Ivano Legnini +13 more
openalex +1 more source
Thermal constraints on in vivo optogenetic manipulations. [PDF]
, 2019 A key assumption of optogenetics is that light only affects opsin-expressing neurons. However, illumination invariably heats tissue, and many physiological processes are temperature-sensitive.
Kreitzer, Anatol C +2 more
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