Results 61 to 70 of about 44,262 (332)
New insights into cochlear sound encoding [version 1; referees: 2 approved]
F1000Research, 2016 The inner ear uses specialized synapses to indefatigably transmit sound information from hair cells to spiral ganglion neurons at high rates with submillisecond precision.
Tobias Moser, Christian Vogl
doaj +1 more source
Bimodal activation of different neuron classes with the spectrally red-shifted channelrhodopsin chimera C1V1 in Caenorhabditis elegans [PDF]
, 2012 The C. elegans nervous system is particularly well suited for optogenetic analyses of circuit function: Essentially all connections have been mapped, and light can be directed at the neuron of interest in the freely moving, transparent animals, while ...
Erbguth, Karen +4 more
core +3 more sources
Advanced Materials, EarlyView.We report a multifunctional tapered optical fiber integrating a conformal micro‐resistance temperature detector (µRTD) for local, real‐time thermometry during optical stimulation. The platform combines light‐delivery and temperature sensing within a minimally invasive footprint, enabling detection of sub‐degree cortical heating under representative ...
Antonio Balena +6 more
wiley +1 more source
Optogenetics: implications for Alzheimer’s disease research and therapy
Molecular Brain, 2022 Alzheimer’s disease (AD), a critical neurodegenerative condition, has a wide range of effects on brain activity. Synaptic plasticity and neuronal circuits are the most vulnerable in Alzheimer’s disease, but the exact mechanism is unknown.
Parsa Mirzayi +4 more
doaj +1 more source
Remote Optogenetics Using Up/Down-Conversion Phosphors
Frontiers in Molecular Biosciences, 2021 Microbial rhodopsins widely used for optogenetics are sensitive to light in the visible spectrum. As visible light is heavily scattered and absorbed by tissue, stimulating light for optogenetic control does not reach deep in the tissue irradiated from ...
Takanori Matsubara, Takayuki Yamashita
doaj +1 more source
Bioelectrical Interfaces Beyond Excitable Cells: Cancer, Aging, and Gene Expression Modulation
Advanced Materials Interfaces, EarlyView.ABSTRACT The investigation of biological conductivity has evolved from its classical foundation based on ionic fluxes underpinning cardiac and neuronal excitability to a multifaceted regulator of cellular physiology. Traditional approaches for probing electrical events in living matter focused largely on action potentials recording.
Paolo Cadinu +14 more
wiley +1 more source
From Lab to Landscape: Environmental Biohybrid Robotics for Ecological Futures
Advanced Robotics Research, EarlyView.This Perspective explores environmental biohybrid robotics, integrating living tissues, microorganisms, and insects for operation in real‐world ecosystems. It traces the leap from laboratory experiments to forests, wetlands, and urban environments and discusses key challenges, development pathways, and opportunities for ecological monitoring and ...
Miriam Filippi
wiley +1 more source
Light‐Driven Quadrupedal Walking Biohybrid Robot With Antagonistic Muscle‐Rings and Inclined Joints
Advanced Robotics Research, EarlyView.This work presents a light‐driven quadrupedal walking biohybrid robot powered by antagonistic muscle‐rings that achieve alternating walking gait. Optical training improved reproducibility of cultured muscle tissues, while caffeine treatment enhanced contractile force.
Shotaro Saito +5 more
wiley +1 more source
Illuminating pathogen-host intimacy through optogenetics.
PLoS Pathogens, 2018 The birth and subsequent evolution of optogenetics has resulted in an unprecedented advancement in our understanding of the brain. Its outstanding success does usher wider applications; however, the tool remains still largely relegated to neuroscience ...
Ruben Dario Arroyo-Olarte +3 more
doaj +1 more source
BioTechniques, 2014 It has been a decade since researchers first showed they could control neurons with light. Jeffrey Perkel takes a look at the technique that changed how we study the brain.
Jeffrey M. Perkel
doaj +1 more source