Results 61 to 70 of about 28,083 (286)
Cells, 2021 Calcium ion channels are involved in numerous biological functions such as lymphocyte activation, muscle contraction, neurotransmission, excitation, hormone secretion, gene expression, cell migration, memory, and aging.
Lena Maltan +3 more
doaj +1 more source
Cell Type-Specific Targeting Strategies for Optogenetics
, 2018 View references (89) Optogenetic techniques allow versatile, cell type-specific light-based control of cellular activity in diverse set of cells, circuits, and brain structures.
Adamantidis, Antoine Roger, Yizhar, Ofer
core +1 more source
Advanced Materials, EarlyView.Spatiotemporal control over cell behavior within bioprinted constructs remains a key challenge in biofabrication. Volumetric bioprinting using multi‐wavelength light sources permits to activate light‐sensitive intracellular proteins as well as optogenetic gene and protein expression circuits in bioprinted cells, in addition to enabling fast printing of
Davide Ribezzi +14 more
wiley +1 more source
Optogenetics: implications for Alzheimer’s disease research and therapy
Molecular Brain, 2022 Alzheimer’s disease (AD), a critical neurodegenerative condition, has a wide range of effects on brain activity. Synaptic plasticity and neuronal circuits are the most vulnerable in Alzheimer’s disease, but the exact mechanism is unknown.
Parsa Mirzayi +4 more
doaj +1 more source
American Journal of Physiology-Heart and Circulatory Physiology, 2013 Optogenetics is an emerging technology for optical interrogation and control of biological function with high specificity and high spatiotemporal resolution. Mammalian cells and tissues can be sensitized to respond to light by a relatively simple and well-tolerated genetic modification using microbial opsins (light-gated ion channels and pumps).
openaire +3 more sources
Advanced Materials, EarlyView.Membrane‐bound multimodal transducers enable longitudinal ultrasound‐guided photoacoustic monitoring and in situ thermal control of CAR T cells in heterogeneous solid tumors. Imaging correlates T cell trafficking with tumor response, distinguishing responders from nonresponders.
Myeongsoo Kim +14 more
wiley +1 more source
Remote Optogenetics Using Up/Down-Conversion Phosphors
Frontiers in Molecular Biosciences, 2021 Microbial rhodopsins widely used for optogenetics are sensitive to light in the visible spectrum. As visible light is heavily scattered and absorbed by tissue, stimulating light for optogenetic control does not reach deep in the tissue irradiated from ...
Takanori Matsubara, Takayuki Yamashita
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Optogenetics in preclinical neuroscience and psychiatry research: recent insights and potential applications [PDF]
, 2014 Ross A McDevitt,1 Sean J Reed,2 Jonathan P Britt2,3 1Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD, USA; 2Integrated Program in Neuroscience, Montreal Neurological Institute, 3Department of ...
Reed SJ, Britt JP, McDevitt RA
core
Advanced Materials, EarlyView.Using a bottom‐up approach, we engineered a human neuromuscular microchip to investigate distinct adaptive responses to neural stimulation and metabolic stress. Further integration of endothelial cells revealed their critical role in modulating neuromuscular excitability, establishing a comprehensive neurovascular‐muscular model.
Jinchul Ahn +17 more
wiley +1 more source
New insights into cochlear sound encoding [version 1; referees: 2 approved]
F1000Research, 2016 The inner ear uses specialized synapses to indefatigably transmit sound information from hair cells to spiral ganglion neurons at high rates with submillisecond precision.
Tobias Moser, Christian Vogl
doaj +1 more source