Results 51 to 60 of about 28,083 (286)

An Ultrasonically-Powered System for 1.06 mm 3 Implantable Optogenetics and Drug Delivery Dust

open access: yes, 2023
International audienceThis paper presents an ultrasonically powered micro-system for deep tissue optogenetic stimulation. The developed system is composed of a Base for Powering and Controlling (BPC) and an implantable Dust for optogenetics and drug ...
Amalric, Marianne   +8 more
core   +1 more source

Temporal Interference Stimulation of Centromedian‐Parafascicular Complex in Disorders of Consciousness: A Pilot Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu   +7 more
wiley   +1 more source

Optogenetics and Vision

open access: yesHerald of the Russian Academy of Sciences, 2019
In this article the authors discuss electronic and optogenetic approaches for degenerative (blind) retina prosthesis as the main strategies for the restoration of vision to blind people. Primary attention is devoted to the prospects of developing retinal prostheses for the blind using modern optogenetic methods, and rhodopsins, which are photosensitive
M. P. Kirpichnikov, М. А. Оstrovsky
openaire   +2 more sources

Nanoengineered Light-Harvested Proteins for Optogenetics and Photopharmacology [PDF]

open access: yes, 2019
Chemical modification with nanometer precision can be used to probe and to improve the function of complex molecular entities, from organic materials to proteins and their assemblies.
Gisela Cabré (8164768)   +13 more
core   +1 more source

Emerging Post‐CMOS Hardware Neurons for Brain‐Inspired Computing: Devices, Circuits, and System Integration

open access: yesAdvanced Functional Materials, EarlyView.
The physical realization of artificial neurons is a critical challenge for energy‐efficient neuromorphic computing. This review presents a comprehensive analysis of the evolution of artificial neuron implementations from conventional CMOS to emerging post‐CMOS technologies.
Kannan Udaya Mohanan   +4 more
wiley   +1 more source

Optogenetics — The Might of Light

open access: yesNew England Journal of Medicine, 2021
Optogenetics Recognized through the Lasker Award This year’s Lasker Basic Medical Research Award goes to Drs.
openaire   +3 more sources

In Vivo Optogenetics Based on Heavy Metal-Free Photon Upconversion Nanoparticles [PDF]

open access: yes
Photon upconversion (UC) from red or near-infrared (NIR) light to blue light is promising for in vivo optogenetics. However, the examples of in vivo optogenetics have been limited to lanthanide inorganic UC nanoparticles, and there have been no examples ...
Jumpei, Kondo   +8 more
core   +2 more sources

Optogenetics: opsins and optical interfaces in neuroscience. [PDF]

open access: yes, 2014
Optogenetics is defined as the integration of optics and genetics to control well-defined events within specified cells of living tissue. In this introduction, we focus on the basic techniques necessary for employing microbial opsins as optogenetic tools
de Lecea, Luis   +3 more
core   +1 more source

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

open access: yesAdvanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou   +6 more
wiley   +1 more source

Soft Skins With Reversible Thickness Morphing: Materials, Mechanisms, and Applications

open access: yesAdvanced Materials, EarlyView.
Evolution of electronic skin (e‐skin) technologies toward adaptive, multifunctional soft skins. Phase I highlights early rigid and discrete sensory interfaces. Phase II shows the transition toward flexible, stretchable, and large‐area e‐skin. Phase III captures the emergence of computational e‐skin.
Oliver Ozioko   +2 more
wiley   +1 more source

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